Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Mouse Peroxisome Proliferator Activated Receptor Delta (PPARd) Polyclonal Antibody | anti-PPARd antibody
Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Delta (PPARd)
MGHHHHHHSGS-NG GPEHTLPSSS CADLSQNSSP SSLLDQLQMG CDGASGGSLN MECRVCGDKA SGFHYGVHAC EGCKGFFRRT IRMKLEYEKC DRICKIQKKN RNKCQYCRFQ KCLALGMSHN AIRFGRM
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
Immunohistochemistry (IHC)
(DABstainingonIHC-P.Samples:MouseTissue))
NCBI and Uniprot Product Information
Uniprot Description
PPAR-delta: Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand. Belongs to the nuclear hormone receptor family. NR1 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Nuclear receptor
Chromosomal Location of Human Ortholog: 17 A3.3|17 14.64 cM
Cellular Component: nuclear chromatin; nucleus
Molecular Function: DNA binding; DNA binding transcription factor activity; drug binding; enzyme activator activity; fatty acid binding; ligand-dependent nuclear receptor activity; lipid binding; metal ion binding; NF-kappaB binding; prostacyclin receptor activity; protein heterodimerization activity; retinoid X receptor binding; sequence-specific DNA binding; steroid hormone receptor activity; transcription coactivator activity; transcription factor binding; zinc ion binding
Biological Process: anagen; apoptosis; axon ensheathment; cell differentiation; cell proliferation; cell-substrate adhesion; cellular process; embryo implantation; epidermis development; fatty acid beta-oxidation; fatty acid oxidation; fatty acid transport; keratinocyte migration; keratinocyte proliferation; lipid metabolic process; mRNA transcription; negative regulation of apoptosis; negative regulation of cell growth; negative regulation of collagen biosynthetic process; negative regulation of epithelial cell proliferation; negative regulation of inflammatory response; negative regulation of myoblast differentiation; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; negative regulation of transcription from RNA polymerase II promoter; phospholipid biosynthetic process; placenta development; positive regulation of cell proliferation; positive regulation of epidermis development; positive regulation of insulin secretion; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of skeletal muscle tissue regeneration; positive regulation of transcription, DNA-templated; proteoglycan metabolic process; regulation of cell proliferation; regulation of fat cell differentiation; regulation of insulin secretion; regulation of skeletal muscle satellite cell proliferation; regulation of transcription, DNA-templated; steroid hormone mediated signaling; transcription, DNA-dependent; vitamin A metabolic process; wound healing
Research Articles on PPARd
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Product Notes
The PPARd ppard (Catalog #AAA2003892) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Peroxisome Proliferator Activated Receptor Delta (PPARd) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Peroxisome Proliferator Activated Receptor Delta (PPARd) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the PPARd ppard for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with N-terminal His-Tag and its sequence is listed below. MGHHHHHHSG S-NG GPEHTLPSSS CADLSQNSSP SSLLDQLQMG CDGASGGSLN MECRVCGDKA SGFHYGVHAC EGCKGFFRRT IRMKLEYEKC DRICKIQKKN RNKCQYCRFQ KCLALGMSHN AIRFGRM. It is sometimes possible for the material contained within the vial of "Peroxisome Proliferator Activated Receptor Delta (PPARd), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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