Rabbit anti-Mouse Peptidoglycan Recognition Protein 1 Polyclonal Antibody | anti-PGLYRP1 antibody
Polyclonal Antibody to Peptidoglycan Recognition Protein 1 (PGLYRP1)
Immunohistochemistry: 5-20 ug/mL;
Immunocytochemistry: 5-20 ug/mL;
Optimal working dilutions must be determined by end user.
Store at 4ºC for frequent use.
Aliquot and store at -20ºC for 24 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Mouse Thymus lysate; Primary Ab: 5ug/ml Rabbit Anti-Mouse PGLYRP1 Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
NCBI and Uniprot Product Information
Uniprot Description
PGLYRP1: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
Protein type: Apoptosis; Receptor, misc.; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 7|7 A3
Cellular Component: cytoplasm; extracellular region; extracellular space
Molecular Function: cytokine activity; N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan binding; peptidoglycan receptor activity; zinc ion binding
Biological Process: apoptosis; defense response to bacterium; defense response to Gram-positive bacterium; detection of bacterium; immune system process; innate immune response; killing of cells of other organism; negative regulation of inflammatory response; negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation involved in immune response; peptidoglycan catabolic process; positive regulation of cytolysis in other organism
Research Articles on PGLYRP1
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Product Notes
The PGLYRP1 pglyrp1 (Catalog #AAA2026756) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Peptidoglycan Recognition Protein 1 (PGLYRP1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Peptidoglycan Recognition Protein 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP). Western blotting: 0.5-5 ug/mL; Immunohistochemistry: 5-20 ug/mL; Immunocytochemistry: 5-20 ug/mL; Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the PGLYRP1 pglyrp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Peptidoglycan Recognition Protein 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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