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Western Blot (WB) (Western Blot analysis of K562 cells using PDP2 Polyclonal Antibody)

Rabbit anti-Human PDP2 Polyclonal Antibody | anti-PDP2 antibody

PDP2 Antibody

Gene Names
PDP2; PPM2C2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PDP2; Polyclonal Antibody; PDP2 Antibody; KIAA1348; [Pyruvate dehydrogenase [acetyl-Transferring]]-phosphatase 2; mitochondrial; PDP 2; Pyruvate dehydrogenase phosphatase catalytic subunit 2; PDPC 2; anti-PDP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Applicable Applications for anti-PDP2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
ELISA: 1:20000
Immunogen
Synthesized peptide derived from the Internal region of human PDP2.
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western Blot analysis of K562 cells using PDP2 Polyclonal Antibody)

Western Blot (WB) (Western Blot analysis of K562 cells using PDP2 Polyclonal Antibody)
Product Categories/Family for anti-PDP2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
59,978 Da
NCBI Official Full Name
[Pyruvate dehydrogenase
NCBI Official Synonym Full Names
pyruvate dehyrogenase phosphatase catalytic subunit 2
NCBI Official Symbol
PDP2
NCBI Official Synonym Symbols
PPM2C2
NCBI Protein Information
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial
UniProt Protein Name
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial
UniProt Gene Name
PDP2
UniProt Synonym Gene Names
KIAA1348; PDP 2; PDPC 2
UniProt Entry Name
PDP2_HUMAN

Uniprot Description

PDP2: a protein phosphoserine phosphatase associated with the mitochondrial matrix that activates phosphorylated pyruvate dehydrogenase complex by dephosphorylation. The PDPs play crucial roles in switching metabolic flux from glycolysis towards oxidative phosphorylation. Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex . PDP2 consists of only a catalytic subunit. Belongs to the PP2C family.

Protein type: Protein phosphatase, Ser/Thr (non-receptor); Mitochondrial; EC 3.1.3.43

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: mitochondrial matrix

Molecular Function: [pyruvate dehydrogenase (lipoamide)] phosphatase activity; magnesium-dependent protein serine/threonine phosphatase activity; metal ion binding

Biological Process: cellular metabolic process; protein amino acid dephosphorylation; pyruvate metabolic process; regulation of acetyl-CoA biosynthetic process from pyruvate

Research Articles on PDP2

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Product Notes

The PDP2 pdp2 (Catalog #AAA7117324) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:20000. Researchers should empirically determine the suitability of the PDP2 pdp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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