Western Blot (WB)
(PDIA2 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PDIA2 antibody detected the PDIA2 protein (arrow).)
Rabbit anti-Human PDIA2 Polyclonal Antibody | anti-PDIA2 antibody
PDIA2, ID (PDIA2, PDIP, Protein disulfide-isomerase A2, Pancreas-specific protein disulfide isomerase) (AP)
Gene Names
PDIA2; PDI; PDA2; PDIP; PDIR
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PDIA2; Polyclonal Antibody; ID (PDIA2; PDIP; Protein disulfide-isomerase A2; Pancreas-specific protein disulfide isomerase) (AP); Pancreas-specific protein disulfide isomerase; anti-PDIA2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-PDIA2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
PDIA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-239 amino acids from the Central region of human PDIA2.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(PDIA2 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PDIA2 antibody detected the PDIA2 protein (arrow).)
Western Blot (WB)
(PDIA2 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PDIA2 antibody detected the PDIA2 protein (arrow).)
Related Product Information for anti-PDIA2 antibody
Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 [PubMed 8561901]).
Product Categories/Family for anti-PDIA2 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Swiatkowska, M., et al. J. Biol. Chem. 285(39):29874-29883(2010). Wang, C., et al. J. Biol. Chem. 285(35):26788-26797(2010). Honjo, Y., et al. Brain Res. 1349, 90-96 (2010): Popescu, N.I., et al. Blood 116(6):993-1001(2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58206 MW
NCBI Official Full Name
protein disulfide-isomerase A2
NCBI Official Synonym Full Names
protein disulfide isomerase family A member 2
NCBI Official Symbol
PDIA2
NCBI Official Synonym Symbols
PDI; PDA2; PDIP; PDIR
NCBI Protein Information
protein disulfide-isomerase A2
UniProt Protein Name
Protein disulfide-isomerase A2
Protein Family
UniProt Gene Name
PDIA2
UniProt Synonym Gene Names
PDIP; PDIp
NCBI Description
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels. [provided by RefSeq, Sep 2017]
Uniprot Description
Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
Research Articles on PDIA2
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Product Notes
The PDIA2 pdia2 (Catalog #AAA6332353) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDIA2, ID (PDIA2, PDIP, Protein disulfide-isomerase A2, Pancreas-specific protein disulfide isomerase) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PDIA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PDIA2 pdia2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDIA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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