Immunohistochemistry (IHC)
(CD71 on Breast Cancer)
Mouse anti-Human CD71 Monoclonal Antibody | anti-CD71 antibody
CD71
Reactivity
Human
Applications
Dilution Range: 1:50-1:200
Synonyms
CD71; Monoclonal Antibody; anti-CD71 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Applicable Applications for anti-CD71 antibody
Dilution Range: 1:50-1:200
Positive Control
Bone Marrow
Immunohistochemistry (IHC)
(CD71 on Breast Cancer)
Immunohistochemistry (IHC)
(CD71 on Breast Cancer)
Related Product Information for anti-CD71 antibody
Cluster of differentiation 71 (CD71), also known as Transferrin Receptor Protein 1 (TfR1) or the transferrin receptor, is a cell surface proliferation marker that is involved in the cellular uptake of iron, and is expressed in placental syncytiotrophoblasts, myocytes, basal keratinocytes, hepatocytes, endocrine pancreas, spermatocytes, and erythroid precursors. CD71 is most highly expressed in early erythroid precursors through the intermediate normoblast phase, after which expression decreases through the reticulocyte phase, and is fully absent from mature erythrocytes; CD71 is therefore highly useful as a marker for erythroid components within bone marrow biopsy specimens, without interference from mature erythrocytes. CD71 expression has been indicated in invasive breast carcinoma with acquired resistance to tamoxifen, and has been linked to poor prognosis in ER+/luminal-like breast cancer. Anti-CD71 is used in the determination of erythroid leukemia, benign erythroid proliferative disorders, and myelodysplastic syndrome.
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Product Notes
The CD71 (Catalog #AAA344118) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD71 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD71 can be used in a range of immunoassay formats including, but not limited to, Dilution Range: 1:50-1:200. Researchers should empirically determine the suitability of the CD71 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD71, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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