Rabbit PDE8A Polyclonal Antibody | anti-PDE8A antibody
PDE8A Antibody FITC-Conjugated
Reactivity
Bovine, Human, Monkey, Mouse, Rat
Applications
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Synonyms
PDE8A; Polyclonal Antibody; PDE8A Antibody FITC-Conjugated; 5''-cyclic phosphodiesterase 8A; cAMP specific cyclic nucleotide phosphodiesterase 8A; FLJ16150; High affinity cAMP specific and IBMX insensitive 3'5' cyclic phosphodiesterase 8A; HsT19550; PDE 8A; Phosphodiesterase 8A; Weakly similar to 3'5'-cyclic-nucleotide phosphodiesterase antibody; anti-PDE8A antibody
Host
Rabbit
Reactivity
Bovine, Human, Monkey, Mouse, Rat
Clonality
Polyclonal
Specificity
This antibody will label only PDE8A variants. This antibody will not cross react with other PDE family members.
Form/Format
FITC-Conjugated
Concentration
0.65 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
305
Applicable Applications for anti-PDE8A antibody
Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Confocal Microscopy||1:250
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:250
Immunofluorescence: 1:250
Immunohistochemistry: 1:250
Immunoprecipitation: 1:250
Western Blot: 1:500-1:2,000
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunocytochemistry: 1:250
Immunofluorescence: 1:250
Immunohistochemistry: 1:250
Immunoprecipitation: 1:250
Western Blot: 1:500-1:2,000
Immunogen
Synthetic cyclic peptide from near the N terminus common to all PDE8A variants.
Expression
Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon.
Determinant
N-epitope
Molecular Function
3', 5'-cyclic-AMP phosphodiesterase activity, Hydrolase, Metal-binding
Structure
Belongs to cyclic nucleotide phosphodiesterase family. PDE8B subfamily. Contains 1 PAC (Pas-associated C-terminal) domain. Contains 1 PAS (PER-ARNT-SIM) domain.
Subcellular Location
Cytosol
Preparation and Storage
-20 degree C for long term storage
Related Product Information for anti-PDE8A antibody
FITC-Conjugated Pan Phosphodiesterase 8A Antibody N-epitope
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
35,111 Da
NCBI Official Full Name
PDE8A protein
UniProt Protein Name
PDE8A protein
UniProt Gene Name
PDE8A
UniProt Entry Name
Q86XV4_HUMAN
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Product Notes
The PDE8A pde8a (Catalog #AAA543572) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE8A Antibody FITC-Conjugated reacts with Bovine, Human, Monkey, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDE8A can be used in a range of immunoassay formats including, but not limited to, Confocal Microscopy (CM), ELISA (EIA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB). Confocal Microscopy||1:250 Dot Blot: 1:10,000 ELISA: 1:10,000 Immunocytochemistry: 1:250 Immunofluorescence: 1:250 Immunohistochemistry: 1:250 Immunoprecipitation: 1:250 Western Blot: 1:500-1:2,000. Researchers should empirically determine the suitability of the PDE8A pde8a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE8A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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