Rabbit PDE6B  Polyclonal Antibody | anti-PDE6B  antibody

PDE6B  Polyclonal Antibody

Cat. Num. AAA2536812

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity Purification
• Synonyms: PDE6B ; Polyclonal Antibody; PDE6B Polyclonal Antibody; rd1; PDEB; RP40; CSNB3; CSNBAD2; anti-PDE6B antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification

• Applicable Applications for anti-PDE6B antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500-1:2000, IHC: 1:50-1:200
• Immunogen: Recombinant protein of human PDE6B
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-30717 / sc-30719
• Preparation and Storage: Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using PDE6B antibody.)

Related Product Information for anti-PDE6B  antibody

Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 958871497
• Molecular Weight: Calculated MW: 98kDa
• NCBI Official Full Name: PDE6B, partial
• UniProt Protein Name: PDE6B
• UniProt Gene Name: PDE6B
• UniProt Entry Name: A0A0S7LVH0_9TELE