Rabbit PDCD5 Polyclonal Antibody | anti-PDCD5 antibody

Rabbit Polyclonal to Human PDCD5

Cat. Num. AAA244798

• Gene Names: PDCD5; TFAR19
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: PDCD5; Polyclonal Antibody; Rabbit Polyclonal to Human PDCD5; Anti-PDCD5 Antibody (C-Terminus) IHC-plus; Programmed cell death 5; Protein TFAR19; TFAR19 novel apoptosis-related; TFAR19; Human PDCD5; anti-PDCD5 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS containing 0.02% sodium azide
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 125

• Applicable Applications for anti-PDCD5 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA, IHC-P (5 ug/ml), WB (1 ug/ml)
• Target Species: Human
• Immunogen Description: A 21 amino acid peptide from near the carboxy terminus of human PDCD5.
• Immunogen Type: Synthetic peptide
• Immunogen: PDCD5 antibody was raised against a 21 amino acid peptide from near the carboxy terminus of human PDCD5.
• Antigen Modification: C-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-PDCD5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-PDCD5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of PDCD5 in Jurkat cells with PDCD5 antibody at 10 ug/ml.)

Immunocytochemistry (ICC)

(Immunocytochemistry of PDCD5 in Jurkat cells with PDCD5 antibody at 2 ug/ml.)

Western Blot (WB)

(Western blot of PDCD5 in EL4 cell lysate with PDCD5 antibody at 1 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 4759224
• NCBI GeneID: 9141
• NCBI Accession #: NP_004699.1
• NCBI GenBank Nucleotide #: NM_004708.3
• UniProt Accession #: O14737; Q53YC9; Q6IB70; B4DE64
• Molecular Weight: 14,997 Da
• NCBI Official Full Name: programmed cell death protein 5
• NCBI Official Synonym Full Names: programmed cell death 5
• NCBI Official Symbol: PDCD5
• NCBI Official Synonym Symbols: TFAR19
• NCBI Protein Information: programmed cell death protein 5; TFAR19 novel apoptosis-related; TF1 cell apoptosis-related gene 19; TF-1 cell apoptosis-related protein 19
• UniProt Protein Name: Programmed cell death protein 5
• Protein Family: Programmed cell death protein
• UniProt Gene Name: PDCD5
• UniProt Synonym Gene Names: TFAR19; Protein TFAR19
• UniProt Entry Name: PDCD5_HUMAN

NCBI Description

This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010]

Uniprot Description

PDCD5: May function in the process of apoptosis. Belongs to the PDCD5 family.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 19q13.11

Cellular Component: cytoplasm; nucleus

Molecular Function: heparin binding; protein binding; DNA binding; beta-tubulin binding

Biological Process: negative regulation of cell proliferation; positive regulation of apoptosis; positive regulation of caspase activity