Western Blot (WB)
(Western blot analysis of PDCD5 in Jurkat cell lysate with PDCD5 antibody at 2.5 ug/mL.)
Rabbit PDCD5 Polyclonal Antibody | anti-PDCD5 antibody
PDCD5 Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunocytochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
PDCD5; Polyclonal Antibody; PDCD5 Antibody; Programmed cell death protein 5; TFAR19; MGC9294; anti-PDCD5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
125
Applicable Applications for anti-PDCD5 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 13 amino acid peptide from near the amino terminus of human PDCD5.
Target Name
PDCD5
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of PDCD5 in Jurkat cell lysate with PDCD5 antibody at 2.5 ug/mL.)
Western Blot (WB)
(Western blot analysis of PDCD5 in Jurkat cell lysate with PDCD5 antibody at 2.5 ug/mL.)
Immunocytochemistry (ICC)
(Immunocytochemistry of PDCD5 in Jurkat cells with PDCD5 antibody at 5 ug/mL.)
Immunocytochemistry (ICC)
(Immunocytochemistry of PDCD5 in Jurkat cells with PDCD5 antibody at 5 ug/mL.)
Related Product Information for anti-PDCD5 antibody
Programmed cell death 5 (PDCD5), a human apoptosis-related protein, is thought to play an early and universal role in apoptosis. PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis, where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 has a compact core structure of low flexibility with two mobile alpha-helices at N-terminal and a flexible unstructured C-terminal region. The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein. PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death. PDCD5 may play a dual role in the Tip60 pathway. It interacts with Tip60 and functions as a Tip60 co-activator to promote apoptosis. The nucleotide polymorphisms in the 5-upstream region of PDCD5 affect promoter activity and the susceptibility of a Chinese population to develop chronic myelogenous leukemia and may represent a novel tumor suppressor gene influencing lung cancer.
Product Categories/Family for anti-PDCD5 antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
14,997 Da
NCBI Official Full Name
PDCD5
UniProt Protein Name
Programmed cell death protein 5
Protein Family
UniProt Gene Name
PDCD5
UniProt Synonym Gene Names
TFAR19; Protein TFAR19
UniProt Entry Name
PDCD5_HUMAN
Uniprot Description
PDCD5: May function in the process of apoptosis. Belongs to the PDCD5 family.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 19q13.11
Cellular Component: cytoplasm; nucleus
Molecular Function: heparin binding; protein binding; DNA binding; beta-tubulin binding
Biological Process: negative regulation of cell proliferation; positive regulation of apoptosis; positive regulation of caspase activity
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Product Notes
The PDCD5 pdcd5 (Catalog #AAA9403150) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDCD5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDCD5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the PDCD5 pdcd5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDCD5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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