Rabbit anti-Human PCF11 Polyclonal Antibody | anti-PCF11 antibody
PCF11 Antibody
Reactivity
Human
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
PCF11; Polyclonal Antibody; PCF11 Antibody; hPCF11; KIAA0824; OTTHUMP00000234826; PCF11 cleavage and polyadenylation factor subunit; cleavage and polyadenylation factor II subunit; homolog; cleavage and polyadenylation factor subunit; homolog (S.; PCF11_HUMAN; PCF11p homolog; Pre-mRNA cleavage complex 2 protein Pcf11; Pre-mRNA cleavage complex II protein Pcf11; anti-PCF11 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
PCF11 Antibody detects endogenous levels of PCF11.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-PCF11 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human PCF11.
Conjugation
Unconjugated
Function
Component of pre-mRNA cleavage complex II.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
173,050 Da
NCBI Official Full Name
pre-mRNA cleavage complex 2 protein Pcf11 isoform 3
NCBI Official Synonym Full Names
PCF11 cleavage and polyadenylation factor subunit
NCBI Official Symbol
PCF11
NCBI Protein Information
pre-mRNA cleavage complex 2 protein Pcf11
UniProt Protein Name
Pre-mRNA cleavage complex 2 protein Pcf11
Protein Family
UniProt Gene Name
PCF11
UniProt Synonym Gene Names
KIAA0824
NCBI Description
The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage. [provided by RefSeq, Oct 2016]
Uniprot Description
PCF11: Component of pre-mRNA cleavage complex II.
Protein type: RNA processing; RNA splicing
Chromosomal Location of Human Ortholog: 11q14.1
Cellular Component: cytoplasm; mitochondrion; mRNA cleavage factor complex; nucleoplasm
Molecular Function: mRNA binding
Biological Process: mRNA 3'-end processing; mRNA cleavage; mRNA polyadenylation; mRNA splicing, via spliceosome; termination of RNA polymerase II transcription
Research Articles on PCF11
Similar Products
Product Notes
The PCF11 pcf11 (Catalog #AAA9630541) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PCF11 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PCF11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the PCF11 pcf11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCF11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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