Rabbit anti-Mouse PCDH18 Polyclonal Antibody | anti-PCDH18 antibody

PCDH18, CT (PCDH18, KIAA1562, Protocadherin-18) (FITC)

Cat. Num. AAA6331377

• Gene Names: PCDH18; PCDH68L
• Reactivity: Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: PCDH18; Polyclonal Antibody; CT (PCDH18; KIAA1562; Protocadherin-18) (FITC); Protocadherin-18; anti-PCDH18 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-PCDH18 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: PCDH18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 969-999 amino acids from the C-terminal region of human PCDH18.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(PCDH18 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PCDH18 antibody detected the PCDH18 protein (arrow).)

Related Product Information for anti-PCDH18 antibody

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain.

Product Categories/Family for anti-PCDH18 antibody

Antibodies; Cadherin

References

Homayouni, R., et al. Biochem. Biophys. Res. Commun. 289(2):539-547(2001). Wolverton, T., et al. Genomics 76 (1-3), 66-72 (2001): Suzuki, S.T. Exp. Cell Res. 261(1):13-18(2000). Nollet, F., et al. J. Mol. Biol. 299(3):551-572(2000). Yagi, T., et al. Genes Dev. 14(10):1169-1180(2000).

NCBI and Uniprot Product Information

• NCBI GI #: 14589929
• NCBI GeneID: 54510
• NCBI Accession #: NP_061908.1
• NCBI GenBank Nucleotide #: NM_019035.3
• UniProt Accession #: Q9HCL0; Q52LS2; A8K7K3; B7ZKT1
• Molecular Weight: 126,149 Da
• NCBI Official Full Name: protocadherin-18
• NCBI Official Synonym Full Names: protocadherin 18
• NCBI Official Symbol: PCDH18
• NCBI Official Synonym Symbols: PCDH68L
• NCBI Protein Information: protocadherin-18; protocadherin 68-like protein
• UniProt Protein Name: Protocadherin-18
• Protein Family: Protocadherin
• UniProt Gene Name: PCDH18
• UniProt Synonym Gene Names: KIAA1562
• UniProt Entry Name: PCD18_HUMAN

NCBI Description

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain. [provided by RefSeq, Jul 2008]

Uniprot Description

PCDH18: Potential calcium-dependent cell-adhesion protein. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q31

Cellular Component: plasma membrane; integral to membrane

Molecular Function: calcium ion binding

Biological Process: brain development; homophilic cell adhesion