Rabbit anti-Human, Mouse PCCB Polyclonal Antibody | anti-PCCB antibody

PCCB (Propionyl-CoA Carboxylase beta Chain, Mitochondrial, PCCase Subunit beta, Propanoyl-CoA:Carbon Dioxide Ligase Subunit beta, DKFZp451E113) (Biotin)

Cat. Num. AAA6388571

• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: PCCB; Polyclonal Antibody; PCCB (Propionyl-CoA Carboxylase beta Chain; Mitochondrial; PCCase Subunit beta; Propanoyl-CoA:Carbon Dioxide Ligase Subunit beta; DKFZp451E113) (Biotin); anti-PCCB antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human PCCB. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
• Sequence Length: 1801

• Applicable Applications for anti-PCCB antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human PCCB, aa1-539 (NP_000523.2).
• Immunogen Sequence: MAAALRVAAVGARLSVLASGLRAAVRSLCSQATSVNERIENKRRTALLGGGQRRIDAQHKRGKLTARERISLLLDPGSFVESDMFVEHRCADFGMAADKNKFPGDSVVTGRGRINGRLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGYADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTNEDVTQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFFNYLPLSSQDPAPVRECHDPSDRLVPELDTIVPLESTKAYNMVDIIHSVVDEREFFEIMPNYAKNIIVGFARMNGRTVGIVGNQPKVASGCLDINSSVKGARFVRFCDAFNIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKAYGGAYDVMSSKHLCGDTNYAWPTAEIAVMGAKGAVEIIFKGHENVEAAQAEYIEKFANPFPAAVRGFVDDIIQPSSTRARICCDLDVLASKKVQRPWRKHANIPL
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(PCCB rabbit polyclonal antibody. Western Blot analysis of PCCB expression in mouse liver.)

Western Blot (WB)

(Western Blot analysis of PCCB expression in transfected 293T cell line by PCCB polyclonal antibody. Lane 1: PCCB transfected lysate (58.2kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-PCCB antibody

PCCB is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits.

Product Categories/Family for anti-PCCB antibody

Antibodies; Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 15559226
• NCBI GeneID: 5096
• NCBI Official Full Name: Homo sapiens propionyl Coenzyme A carboxylase, beta polypeptide, mRNA
• NCBI Official Synonym Full Names: propionyl-CoA carboxylase subunit beta
• NCBI Official Symbol: PCCB
• NCBI Protein Information: propionyl-CoA carboxylase beta chain, mitochondrial
• Protein Family: Phycoerythrocyanin

NCBI Description

The protein encoded by this gene is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. This gene encodes the beta subunit of PCC. Defects in this gene are a cause of propionic acidemia type II (PA-2). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]