Mouse anti-Human PCBP3 Polyclonal Antibody | anti-PCBP3 antibody

PCBP3 (Poly(rC)-binding Protein 3, ALPHA-CP3)

Cat. Num. AAA6006195

• Gene Names: PCBP3; ALPHA-CP3
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: PCBP3; Polyclonal Antibody; PCBP3 (Poly(rC)-binding Protein 3; ALPHA-CP3); Anti -PCBP3 (Poly(rC)-binding Protein 3; anti-PCBP3 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human PCBP3.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGSSERQITITGTPANISLAQYLINARLTSEVTGMGTL

• Applicable Applications for anti-PCBP3 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human PCBP3, aa1-313 (AAH12061.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of PCBP3 expression in transfected 293T cell line by PCBP3 polyclonal antibody. Lane 1: PCBP3 transfected lysate (34.43kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-PCBP3 antibody

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC.

Product Categories/Family for anti-PCBP3 antibody

Antibodies; Abs to Binding Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 194306633
• NCBI GeneID: 54039
• NCBI Accession #: NP_001123613.1
• NCBI GenBank Nucleotide #: NM_001130141.1
• UniProt Accession #: P57721; Q8N9K6; Q96EP6; A8MPS2; A8MQ26; B7WNN9; B7WPC1
• Molecular Weight: 39,465 Da
• NCBI Official Full Name: poly(rC)-binding protein 3 isoform 2
• NCBI Official Synonym Full Names: poly(rC) binding protein 3
• NCBI Official Symbol: PCBP3
• NCBI Official Synonym Symbols: ALPHA-CP3
• NCBI Protein Information: poly(rC)-binding protein 3; poly(rC)-binding protein 3
• UniProt Protein Name: Poly(rC)-binding protein 3
• Protein Family: Poly(rC)-binding protein
• UniProt Gene Name: PCBP3
• UniProt Entry Name: PCBP3_HUMAN

NCBI Description

This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Uniprot Description

PCBP3: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial; RNA-binding

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: ribonucleoprotein complex; cytosol; nucleus

Molecular Function: DNA binding; RNA binding

Biological Process: mRNA metabolic process