Western Blot (WB)
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal intestines tissue lysate, Primary antibody: 162018(PBOV1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Rabbit anti-Human PBOV1 Polyclonal Antibody | anti-PBOV1 antibody
PBOV1 Rabbit pAb
Gene Names
PBOV1; UC28; UROC28; dJ171N11.2
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
PBOV1; Polyclonal Antibody; PBOV1 Rabbit pAb; UC28; UROC28; dJ171N11.2; anti-PBOV1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-PBOV1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
Immunogen
Synthetic peptide of human PBOV1
Conjugation
Unconjugated
Molecular Function
UROC28, also known as PBOV1 (prostate and breast cancer overexpressed 1) or UC28, is a 135 amino acid cytoplasmic and nuclear protein that is expressed in colon, prostate, small intestine, testis and spleen, with lower expression in thymus, ovary and peripheral blood leukocytes. UROC28 is up-regulated in prostate, breast and bladder cancer, and is thereby considered a useful target for test and treatment of these cancers. UROC28 is encoded by a gene located on human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Modification
Unmodified
Cell Position
Cytoplasm, Nucleus
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal intestines tissue lysate, Primary antibody: 162018(PBOV1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Western Blot (WB)
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Human fetal intestines tissue lysate, Primary antibody: 162018(PBOV1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 162018(PBOV1 Antibody) at dilution 1/20. (Original magnification: ×200))
Immunohistochemistry (IHC)
(The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 162018(PBOV1 Antibody) at dilution 1/20. (Original magnification: ×200))
Product Categories/Family for anti-PBOV1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16kDa
NCBI Official Full Name
prostate and breast cancer overexpressed gene 1 protein
NCBI Official Synonym Full Names
prostate and breast cancer overexpressed 1
NCBI Official Symbol
PBOV1
NCBI Official Synonym Symbols
UC28; UROC28; dJ171N11.2
NCBI Protein Information
prostate and breast cancer overexpressed gene 1 protein
UniProt Protein Name
Prostate and breast cancer overexpressed gene 1 protein
Protein Family
UniProt Gene Name
PBOV1
UniProt Synonym Gene Names
UROC28; UC28
UniProt Entry Name
PBOV1_HUMAN
NCBI Description
This intronless gene encodes a protein of unknown function. Its expression is up-regulated in some types of cancer, including prostate, breast, and bladder cancer. [provided by RefSeq, Aug 2011]
Uniprot Description
PBOV1:
Chromosomal Location of Human Ortholog: 6q23.3
Cellular Component: cytoplasm; nucleus
Research Articles on PBOV1
Similar Products
Product Notes
The PBOV1 pbov1 (Catalog #AAA4754855) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PBOV1 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PBOV1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the PBOV1 pbov1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PBOV1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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