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Rabbit PARP7 Polyclonal Antibody | anti-TIPARP antibody

PARP7 Antibody

Gene Names
TIPARP; PARP7; ARTD14; pART14
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
PARP7; Polyclonal Antibody; PARP7 Antibody; ADP-ribosyltransferase diphtheria toxin-like 14; ARTD14; AW558171; DDF1; DKFZp434J214; DKFZp686N0351; DKFZp686P1838; FLJ40466; PARP 1; PARP 7; PARP-7; PARPT_HUMAN; pART14; Poly [ADP ribose] polymerase 7; Poly [ADP-ribose] polymerase 7; TCDD inducible poly(ADP ribose) polymerase; TCDD-inducible poly [ADP-ribose] polymerase; TIPARP; anti-TIPARP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
PARP7 Antibody detects endogenous levels of total PARP7.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-TIPARP antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Post Translational Modifications
Auto-mono-ADP-ribosylated.
Subunit Structure
Interacts with AHR.
Function
ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins. Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-TIPARP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,227 Da
NCBI Official Full Name
TCDD-inducible poly
NCBI Official Synonym Full Names
TCDD-inducible poly(ADP-ribose) polymerase
NCBI Official Symbol
TIPARP
NCBI Official Synonym Symbols
PARP7; ARTD14; pART14
NCBI Protein Information
TCDD-inducible poly [ADP-ribose] polymerase; TCDD-inducible poly [ADP-ribose] polymerase; poly [ADP-ribose] polymerase 7; ADP-ribosyltransferase diphtheria toxin-like 14
UniProt Protein Name
TCDD-inducible poly [ADP-ribose] polymerase
UniProt Gene Name
TIPARP
UniProt Synonym Gene Names
PARP7; ARTD14; PARP-7
UniProt Entry Name
PARPT_HUMAN

NCBI Description

This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Uniprot Description

TIPARP: Poly [ADP-ribose] polymerase using NAD(+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.

Protein type: EC 2.4.2.30; Transferase

Chromosomal Location of Human Ortholog: 3q25.31

Cellular Component: nucleus

Molecular Function: metal ion binding; NAD+ ADP-ribosyltransferase activity

Biological Process: estrogen metabolic process; androgen metabolic process; platelet-derived growth factor receptor signaling pathway; palate development; multicellular organismal metabolic process; post-embryonic development; smooth muscle development; protein amino acid ADP-ribosylation; nitrogen compound metabolic process; skeletal morphogenesis; positive regulation of protein catabolic process; hemopoiesis; kidney development; vasculogenesis; female gonad development

Research Articles on TIPARP

Similar Products

Product Notes

The TIPARP tiparp (Catalog #AAA9629651) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PARP7 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PARP7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the TIPARP tiparp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARP7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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