Rabbit anti-Mouse PARP, Cleaved Polyclonal Antibody
PARP, Cleaved (Poly [ADP-ribose] Polymerase 1, PARP-1, ADP-ribosyltransferase Diphtheria Toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] Synthase 1, msPARP, Parp1, Adprp, Adprt, Adprt1)
Reactivity
Mouse
Applications
Western Blot, Immunocytochemistry
Purity
Affinity PurifiedPurified by affinity chromatography.
Synonyms
PARP; Cleaved; Polyclonal Antibody; Cleaved (Poly [ADP-ribose] Polymerase 1; PARP-1; ADP-ribosyltransferase Diphtheria Toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] Synthase 1; msPARP; Parp1; Adprp; Adprt; Adprt1); Anti -PARP; anti-PARP; Cleaved antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse PARP at ~89kD.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 1% BSA, 0.02% thimerosal, 50% glycerol.
Applicable Applications for anti-PARP, Cleaved antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
Suitable for use in Western Blot and Immunocytochemistry.
Dilution: Western Blot: 0.5-4ug/ml
Immunocytochemistry: 10-20ug/ml
Dilution: Western Blot: 0.5-4ug/ml
Immunocytochemistry: 10-20ug/ml
Immunogen
Synthetic peptide corresponding to Asp214 from mouse PARP at C-terminus.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-PARP, Cleaved antibody
PARP, a 116kD nuclear poly (ADP-ribose) polymerase, is a highly conserved nuclear enzyme implicated in DNA repair and in the apoptosis response of cells. This protein can be cleaved by many caspases in vitro and is one of the main cleavage targets of caspase-3 in vivo. The cleavege occurs between ASP214 and Gly 215, which separates PARP's N-terminal DNA binding domain (24kD) from its C-terminal catalytic domain (89kD). It has been shown that cleavage of PARP facilitates cellular disassembly and inhibition of PARP cleavage attenuates apoptosis in vitro.
Product Categories/Family for anti-PARP, Cleaved antibody
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Product Notes
The PARP, Cleaved (Catalog #AAA6004061) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PARP, Cleaved (Poly [ADP-ribose] Polymerase 1, PARP-1, ADP-ribosyltransferase Diphtheria Toxin-like 1, ARTD1, NAD(+) ADP-ribosyltransferase 1, ADPRT 1, Poly[ADP-ribose] Synthase 1, msPARP, Parp1, Adprp, Adprt, Adprt1) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PARP, Cleaved can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Suitable for use in Western Blot and Immunocytochemistry. Dilution: Western Blot: 0.5-4ug/ml Immunocytochemistry: 10-20ug/ml. Researchers should empirically determine the suitability of the PARP, Cleaved for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARP, Cleaved, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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