Rabbit anti-Human, Mouse PARD3B Polyclonal Antibody | anti-PARD3B antibody
PARD3B Antibody
Gene Names
PARD3B; PAR3B; PAR3L; PAR3LC; Par3Lb; ALS2CR19; PAR3beta
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
PARD3B; Polyclonal Antibody; PARD3B Antibody; ALS2CR19; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 19; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein; Par 3 partitioning defective 3 homolog B; PAR3-beta; PAR3-L protein; PAR3B; PAR3beta; PAR3L; PAR3L_HUMAN; PAR3LC; Pard3b; Partitioning defective 3 beta; Partitioning defective 3 homolog B; Partitioning defective 3-like protein; anti-PARD3B antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
PARD3B Antibody detects endogenous levels of PARD3B.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-PARD3B antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human PARD3B.
Conjugation
Unconjugated
Similarity
The N-terminal part (1-351) part blocks the association of the tight junction marker TJP1 with the cell-cell boundary when it is overexpressed. Belongs to the PAR3 family.
Subunit Structure
Interacts with PARD6B. Interacts with INSC/inscuteable.
Tissue Specificity
Highly expressed in kidney, lung and skeletal muscle. Expressed at intermediate levels in brain, heart, placenta, liver and pancreas. Isoform 1 is predominant, while isoform 2 and isoform 3 are expressed at lower levels.
Function
Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions.
Note
Partially localized along the cell-cell contact region. Colocalizes with TJP1 to epithelial tight junctions.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-PARD3B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
132,494 Da
NCBI Official Full Name
partitioning defective 3 homolog B isoform c
NCBI Official Synonym Full Names
par-3 family cell polarity regulator beta
NCBI Official Symbol
PARD3B
NCBI Official Synonym Symbols
PAR3B; PAR3L; PAR3LC; Par3Lb; ALS2CR19; PAR3beta
NCBI Protein Information
partitioning defective 3 homolog B; PAR3-beta; PAR3-L protein; partitioning-defective 3-beta; partitioning defective 3-like protein; par-3 partitioning defective 3 homolog B; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 19; amyo
UniProt Protein Name
Partitioning defective 3 homolog B
Protein Family
UniProt Gene Name
PARD3B
UniProt Synonym Gene Names
ALS2CR19; PAR3B; PAR3L; PAR3-L protein
UniProt Entry Name
PAR3L_HUMAN
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Product Notes
The PARD3B pard3b (Catalog #AAA9630453) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PARD3B Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PARD3B can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the PARD3B pard3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARD3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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