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Western Blot (WB) (Western blot analysis of PABPC5 expression in U87MG (A), K562 (B) whole cell lysates.)

Rabbit anti-Human PABPC5 Polyclonal Antibody | anti-PABPC5 antibody

Anti-PABPC5 Antibody

Gene Names
PABPC5; PABP5
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was purified by affinity chromatography.
Synonyms
PABPC5; Polyclonal Antibody; Anti-PABPC5 Antibody; PABP5; Polyadenylate-binding protein 5; PABP-5; Poly(A)-binding protein 5; anti-PABPC5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of PABPC5 protein.
Purity/Purification
The antibody was purified by affinity chromatography.
Form/Format
Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% Sodium Azide.
Sequence Length
382
Applicable Applications for anti-PABPC5 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PABPC5. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of PABPC5 expression in U87MG (A), K562 (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of PABPC5 expression in U87MG (A), K562 (B) whole cell lysates.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of PABPC5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of PABPC5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Related Product Information for anti-PABPC5 antibody
Rabbit polyclonal antibody to PABPC5

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
39,941 Da
NCBI Official Full Name
Polyadenylate-binding protein 5
NCBI Official Synonym Full Names
poly(A) binding protein cytoplasmic 5
NCBI Official Symbol
PABPC5
NCBI Official Synonym Symbols
PABP5
NCBI Protein Information
polyadenylate-binding protein 5
UniProt Protein Name
Polyadenylate-binding protein 5
UniProt Gene Name
PABPC5
UniProt Synonym Gene Names
PABP5; PABP-5; Poly(A)-binding protein 5
UniProt Entry Name
PABP5_HUMAN

NCBI Description

This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]

Uniprot Description

PABPC5: Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: Xq21.3

Cellular Component: mitochondrial matrix

Molecular Function: nucleotide binding; RNA binding

Research Articles on PABPC5

Similar Products

Product Notes

The PABPC5 pabpc5 (Catalog #AAA8242560) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PABPC5 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PABPC5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western Blot: (1/500 - 1/1000); Immunohistochemistry: (1/100 - 1/200). Researchers should empirically determine the suitability of the PABPC5 pabpc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PABPC5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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