Rabbit anti-Human PABPC5 Polyclonal Antibody | anti-PABPC5 antibody

PABPC5 Antibody

Cat. Num. AAA9506700

• Gene Names: PABPC5; PABP5
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Synonyms: PABPC5; Polyclonal Antibody; PABPC5 Antibody; anti-PABPC5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: PABPC5 Antibody detects endogenous levels of total PABPC5 protein.
• Purity/Purification: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 350

• Applicable Applications for anti-PABPC5 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500~1:1000; ELISA: 1:10000
• Target Modification: Unmodified/Total
• Immunogen: The antiserum was produced against synthesized peptide derived from human PABPC5.
• Immunogen Range: 184-233
• Preparation and Storage: Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of lysates from K562 cells, using PABPC5 Antibody. The lane on the right is blocked with the synthesized peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 18201888
• NCBI GeneID: 140886
• NCBI Accession #: NP_543022.1
• NCBI GenBank Nucleotide #: NM_080832.2
• UniProt Accession #: Q96DU9; Q5JQF4; Q6P529; Q9UFE5; A8K240
• Molecular Weight: 43 kDa
• NCBI Official Full Name: polyadenylate-binding protein 5
• NCBI Official Synonym Full Names: poly(A) binding protein cytoplasmic 5
• NCBI Official Symbol: PABPC5
• NCBI Official Synonym Symbols: PABP5
• NCBI Protein Information: polyadenylate-binding protein 5
• UniProt Protein Name: Polyadenylate-binding protein 5
• Protein Family: Polyadenylate-binding protein
• UniProt Gene Name: PABPC5
• UniProt Synonym Gene Names: PABP5; PABP-5; Poly(A)-binding protein 5

NCBI Description

This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]

Uniprot Description

Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo ().