Western Blot (WB)
(Western blot analysis using p53 antibody. Lane1: HT29 cells; Lane 2: MDA-MB-435 cells; Lane 3: K562 cells; Lane 4: COLO205 cells.)
Rabbit p53 Polyclonal Antibody | anti-p53 antibody
p53 Antibody
Gene Names
TP53; P53; BCC7; LFS1; BMFS5; TRP53
Applications
Western Blot
Purity
Affinity Chromatography
Synonyms
p53; Polyclonal Antibody; p53 Antibody; Rabbit Polyclonal p53 Antibody; Polyclonal p53 antibody; Anti-p53 antibody; Phosphoprotein p53 antibody; TP53 antibody; transformation-related protein 53 antibody; TRP53 antibody; tumor protein p53 antibody; Tumor suppressor p53 antibody; Antigen NY-CO-13 antibody; Cellular tumor antigen p53 antibody; FLJ92943 antibody; LFS1 antibody; P53 antibody; p53 antigen antibody; p53 transformation suppressor antibody; p53 tumor suppressor antibody; anti-p53 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
p53 antibody detects endogenous levels of total p53 protein
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
393
Applicable Applications for anti-p53 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
p53 antibody was raised in Rabbit using a synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine 315 (S-S-SP-P-Q) as the immunogen.
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis using p53 antibody. Lane1: HT29 cells; Lane 2: MDA-MB-435 cells; Lane 3: K562 cells; Lane 4: COLO205 cells.)
Western Blot (WB)
(Western blot analysis using p53 antibody. Lane1: HT29 cells; Lane 2: MDA-MB-435 cells; Lane 3: K562 cells; Lane 4: COLO205 cells.)
Related Product Information for anti-p53 antibody
p53 can activate DNA repair proteins when DNA has sustained damage. Thus, it may be an important factor in aging.
Product Categories/Family for anti-p53 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
P53
NCBI Official Synonym Full Names
tumor protein p53
NCBI Official Symbol
TP53
NCBI Official Synonym Symbols
P53; BCC7; LFS1; BMFS5; TRP53
NCBI Protein Information
cellular tumor antigen p53
Protein Family
NCBI Description
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Research Articles on p53
Similar Products
Product Notes
The p53 (Catalog #AAA5313863) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's p53 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the p53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p53, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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