Western Blot (WB)
(Western blot analysis of Mouse brain cell lysates showing detection of ING1 protein using Rabbit Anti-ING1 Polyclonal Antibody (SPC-145). Primary Antibody: Rabbit Anti-ING1 Polyclonal Antibody (SPC-145) at 1:1000. Left: cell expressed DYKDDDDK-tag. Right: Untagged.)
Rabbit anti-Human, Mouse p33 ING1 Polyclonal Antibody | anti-Ing1 antibody
p33 ING1 Antibody: ATTO 594
Gene Names
Ing1; mING1h; p33Ing1; AA407184; AI875420; p37Ing1b; 2610028J21Rik
Reactivity
Human, Mouse
Applications
Western Blot, ELISA, Immunofluorescence
Synonyms
p33 ING1; Polyclonal Antibody; p33 ING1 Antibody: ATTO 594; growth inhibitor ING1; ING1; inhibitor of growth 1; p24ING1c; p33; p33ING; p33ING1b; p33ING1c; p47; p47ING1a; tumor supressor ING1; anti-Ing1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
250ug/mL (varies by lot)
Sequence Length
279
Applicable Applications for anti-Ing1 antibody
Western Blot (WB), ELISA (EIA), Immunofluorescence (IF)
Application Notes
1ug/mL (WB)
Conjugate
ATTO 594
Storage Buffer
TBS, 50% glycerol, 0.09% sodium azide
Preparation and Storage
-20 degree C
Western Blot (WB)
(Western blot analysis of Mouse brain cell lysates showing detection of ING1 protein using Rabbit Anti-ING1 Polyclonal Antibody (SPC-145). Primary Antibody: Rabbit Anti-ING1 Polyclonal Antibody (SPC-145) at 1:1000. Left: cell expressed DYKDDDDK-tag. Right: Untagged.)
Western Blot (WB)
(Western blot analysis of Mouse brain cell lysates showing detection of ING1 protein using Rabbit Anti-ING1 Polyclonal Antibody (SPC-145). Primary Antibody: Rabbit Anti-ING1 Polyclonal Antibody (SPC-145) at 1:1000. Left: cell expressed DYKDDDDK-tag. Right: Untagged.)
Related Product Information for anti-Ing1 antibody
Background Info: Detects a ~33kDa protein corresponding to the molecular mass of p33 ING1 on SDS PAGE immunoblots. Not cross-reactive with any other ING family.
Scientific Background: The p33ING1 protein encodes a 33-kD, 294-amino acid protein that displays the characteristics of a tumor suppressor gene. The p33ING1 protein is a regulator of cell cycle, senescence, and apoptosis. It can mediate growth arrest, anchor dependent growth and influence chemo sensitivity (1-4). It also has a proposed role as a growth regulator, which is consistent with its location in the nucleus (5). It has been demonstrated that the ING1 gene has three exons and that four mRNA variants are transcribed from three different promoter regions (p33 ING1, p24 ING1, p27 ING1, p47 IG1) (6, 7). ING1 can possibly influence the above biological functions depending on which variant is expressed (1-4).
Scientific Background: The p33ING1 protein encodes a 33-kD, 294-amino acid protein that displays the characteristics of a tumor suppressor gene. The p33ING1 protein is a regulator of cell cycle, senescence, and apoptosis. It can mediate growth arrest, anchor dependent growth and influence chemo sensitivity (1-4). It also has a proposed role as a growth regulator, which is consistent with its location in the nucleus (5). It has been demonstrated that the ING1 gene has three exons and that four mRNA variants are transcribed from three different promoter regions (p33 ING1, p24 ING1, p27 ING1, p47 IG1) (6, 7). ING1 can possibly influence the above biological functions depending on which variant is expressed (1-4).
Product Categories/Family for anti-Ing1 antibody
References
1. Cheung, K.J., Jr. and Li, G. (2002) Int. J. Oncol. 21(6): 1361-1365. 2. Cheung, K.J., Jr. and Li, G. (2002) Exp. Cell Res. 279(2): 291-28. 3. Cheung, K.J., Jr. and Li, G. (2002) Int. J. Oncol. 20(6):1319-1322. 4. Cheung, K.J., Jr. and Li, G. (2001) Exp. Cell Res. 268(1): 1-6. 5. Garkavtsev, I. et al. (1996). Nat Genet. 14 (4): 415-420. 6. Gunduz, M. et al. (2000). Cancer Res. 60 (12): 3143-6. 7. Jager, D. et al. (1999). Cancer Res. 59: 6197- 6204.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,968 Da
NCBI Official Full Name
inhibitor of growth protein 1
NCBI Official Synonym Full Names
inhibitor of growth family, member 1
NCBI Official Symbol
Ing1
NCBI Official Synonym Symbols
mING1h; p33Ing1; AA407184; AI875420; p37Ing1b; 2610028J21Rik
NCBI Protein Information
inhibitor of growth protein 1
UniProt Protein Name
Inhibitor of growth protein 1
Protein Family
UniProt Gene Name
Ing1
UniProt Entry Name
ING1_MOUSE
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Product Notes
The Ing1 ing1 (Catalog #AAA805353) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The p33 ING1 Antibody: ATTO 594 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's p33 ING1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunofluorescence (IF). 1ug/mL (WB). Researchers should empirically determine the suitability of the Ing1 ing1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p33 ING1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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