Testing Data
(Gel: 10%SDS-PAGELane1: Hela cell lysateLane2: 293T cell lysateLysates: 40 ug per lanePrimary antibody: 1/500 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 1 minute)
Rabbit anti-Human P2RY11 Polyclonal Antibody | anti-P2RY11 antibody
P2RY11 Antibody
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100
Testing Data
(Gel: 10%SDS-PAGELane1: Hela cell lysateLane2: 293T cell lysateLysates: 40 ug per lanePrimary antibody: 1/500 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 1 minute)
Testing Data
(Gel: 10%SDS-PAGELane1: Hela cell lysateLane2: 293T cell lysateLysates: 40 ug per lanePrimary antibody: 1/500 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 1 minute)
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 31254 (P2RY11 Antibody) at dilution 1/40, on the right is treated with the synthetic peptide.)
Immunohistochemistry (IHC)
(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 31254 (P2RY11 Antibody) at dilution 1/40, on the right is treated with the synthetic peptide.)
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [provided by RefSeq, Jul 2008]
Uniprot Description
P2RY11: Receptor for ATP and ADP coupled to G-proteins that activate both phosphatidylinositol-calcium and adenylyl cyclase second messenger systems. Not activated by UTP or UDP. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: ATP-activated nucleotide receptor activity; purinergic nucleotide receptor activity, G-protein coupled; receptor activity; neurotransmitter receptor activity
Biological Process: synaptic transmission; G-protein coupled receptor protein signaling pathway; adenylate cyclase activation; calcium-mediated signaling; defense response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); adenosine receptor signaling pathway
Research Articles on P2RY11
Similar Products
Product Notes
The P2RY11 p2ry11 (Catalog #AAA9411788) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The P2RY11 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's P2RY11 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-1:5000 Western blotting: 1:200-1:1000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the P2RY11 p2ry11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P2RY11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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