Western Blot (WB)
(WB Suggested Anti-P2RXL1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate)
Rabbit P2RXL1 Polyclonal Antibody | anti-P2RX6 antibody
P2RXL1 antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-P2RXL1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate)
Western Blot (WB)
(WB Suggested Anti-P2RXL1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate)
Target Description: P2RXL1 encodes a protein in the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. P2RXL1 is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]
Uniprot Description
P2X6: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, cation; Receptor, misc.; Channel, ligand-gated
Chromosomal Location of Human Ortholog: 22q11.21
Cellular Component: cell soma; integral to plasma membrane; postsynaptic density; cytoplasm; dendritic spine; integral to nuclear inner membrane; cell junction
Molecular Function: identical protein binding; transmembrane receptor activity; channel activity; purinergic nucleotide receptor activity; ATP binding; ATP-gated cation channel activity
Biological Process: muscle contraction; transport; protein heterooligomerization; signal transduction; transmembrane transport; protein homooligomerization; cation transport
Research Articles on P2RX6
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Product Notes
The P2RX6 p2rx6 (Catalog #AAA3202462) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The P2RXL1 antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's P2RXL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the P2RX6 p2rx6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: ERDLEPQFSI ITKLKGVSVT QIKELGNRLW DVADFVKPPQ GENVFFLVTN. It is sometimes possible for the material contained within the vial of "P2RXL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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