Western Blot (WB)
(P2RX5 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the P2RX5 antibody detected the P2RX5 protein (arrow).)
Rabbit anti-Human P2RX5 Polyclonal Antibody | anti-P2RX5 antibody
P2RX5 Antibody (C-term)
Western Blot (WB)
(P2RX5 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the P2RX5 antibody detected the P2RX5 protein (arrow).)
Western Blot (WB)
(P2RX5 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the P2RX5 antibody detected the P2RX5 protein (arrow).)
Immunohistochemistry (IHC)
(P2RX5 Antibody (C-term) (MBS9214484)immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of P2RX5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(P2RX5 Antibody (C-term) (MBS9214484)immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of P2RX5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
purinoceptors for ATP. This receptor functions as a ligand-gated
ion channel. Several characteristic motifs of ATP-gated channels
are present in its primary structure, but, unlike other members of
the purinoceptors family, this receptor has only a single
transmembrane domain. Three transcript variants encoding distinct
isoforms have been identified for this gene.
Overes, I.M., et al. Cancer Immunol. Immunother. 58(3):429-439(2009)
Dubyak, G.R. Mol. Pharmacol. 72(6):1402-1405(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Duckwitz, W., et al. J. Biol. Chem. 281(51):39561-39572(2006)
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3). [provided by RefSeq, Mar 2011]
Uniprot Description
P2X5: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 17p13.3
Cellular Component: integral to plasma membrane; integral to nuclear inner membrane
Molecular Function: transmembrane receptor activity; ion channel activity; purinergic nucleotide receptor activity; ATP binding; ATP-gated cation channel activity
Biological Process: nervous system development; transport; positive regulation of calcium-mediated signaling; signal transduction; cation transport
Research Articles on P2RX5
Similar Products
Product Notes
The P2RX5 p2rx5 (Catalog #AAA9214484) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 325-353. The P2RX5 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's P2RX5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the P2RX5 p2rx5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P2RX5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
