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Western Blot (WB) (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Human bladder tissue, Human bladder transitional cell carcinoma tissue, Primary antibody: 861996(P2RX3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes)

Rabbit anti-Human P2RX3 Polyclonal Antibody | anti-P2RX3 antibody

P2RX3 Rabbit pAb

Gene Names
P2RX3; P2X3
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
P2RX3; Polyclonal Antibody; P2RX3 Rabbit pAb; purinergic receptor P2X; ligand-gated ion channel; 3; anti-P2RX3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-P2RX3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
IHC: 1:25-1:100
Immunogen
Synthetic peptide of human P2RX3
Conjugation
Unconjugated
Modification
Unmodified
Cell Position
Membrane
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Human bladder tissue, Human bladder transitional cell carcinoma tissue, Primary antibody: 861996(P2RX3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes)

Western Blot (WB) (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Human bladder tissue, Human bladder transitional cell carcinoma tissue, Primary antibody: 861996(P2RX3 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 861996(P2RX3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 861996(P2RX3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 861996(P2RX3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 861996(P2RX3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200))
Product Categories/Family for anti-P2RX3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44,289 Da
NCBI Official Full Name
P2X purinoceptor 3
NCBI Official Synonym Full Names
purinergic receptor P2X, ligand gated ion channel, 3
NCBI Official Symbol
P2RX3
NCBI Official Synonym Symbols
P2X3
NCBI Protein Information
P2X purinoceptor 3; ATP receptor; P2X receptor, subunit 3; purinergic receptor P2X, ligand-gated ion channel, 3; purinergic receptor P2X3; purinoceptor P2X3
UniProt Protein Name
P2X purinoceptor 3
Protein Family
UniProt Gene Name
P2RX3
UniProt Synonym Gene Names
P2X3
UniProt Entry Name
P2RX3_HUMAN

Uniprot Description

P2X3: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.

Protein type: Membrane protein, multi-pass; Channel, ligand-gated; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12

Cellular Component: Golgi apparatus; cell soma; rough endoplasmic reticulum; integral to plasma membrane; dendritic spine; terminal button; integral to nuclear inner membrane; receptor complex; lipid raft

Molecular Function: ATP binding; purinergic nucleotide receptor activity; ATP-gated cation channel activity

Biological Process: urinary bladder smooth muscle contraction; peristalsis; sensory perception of taste; generation of action potential; regulation of synaptic plasticity; positive regulation of calcium-mediated signaling; signal transduction; response to ATP; response to carbohydrate stimulus; behavioral response to pain; transport; response to heat; response to mechanical stimulus; response to hypoxia; neuromuscular synaptic transmission; response to cold; protein homooligomerization

Similar Products

Product Notes

The P2RX3 p2rx3 (Catalog #AAA4758498) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The P2RX3 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's P2RX3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC: 1:25-1:100. Researchers should empirically determine the suitability of the P2RX3 p2rx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P2RX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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