Rabbit OXER1 Polyclonal Antibody | anti-OXER1 antibody

Rabbit Polyclonal to Human OXER1

Cat. Num. AAA247372

• Gene Names: OXER1; GPCR; GPR170; TG1019
• Reactivity: Gorilla, Human
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: OXER1; Polyclonal Antibody; Rabbit Polyclonal to Human OXER1; Anti-OXER1 Antibody (C-Terminus) IHC-plus; GPR170; G-protein coupled receptor 170; HEOAD54; Oxoeicosanoid (OXE) receptor 1; Oxoeicosanoid receptor 1; TG1019; Human OXER1; anti-OXER1 antibody

• Host: Rabbit
• Reactivity: Gorilla, Human
• Clonality: Polyclonal
• Specificity: Human OXER1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except MLEC (61%).
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 423

• Applicable Applications for anti-OXER1 antibody: Immunohistochemistry (IHC - Paraffin)
• Application Notes: IHC-P (15 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic 18 amino acid peptide from C-terminus of human OXER1. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (89%).
• Immunogen Type: Synthetic peptide
• Immunogen: OXER1 antibody was raised against synthetic 18 amino acid peptide from C-terminus of human OXER1. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (89%).
• Antigen Modification: C-Terminus
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-OXER1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-OXER1 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-OXER1 antibody

OXER1 is a Chemoattractant Receptor for eosinophils and neutrophils.

Product Categories/Family for anti-OXER1 antibody

Family: GPCR; Subfamily: Chemoattractant

NCBI and Uniprot Product Information

• NCBI GI #: 22507376
• NCBI GeneID: 165140
• NCBI Accession #: NP_683765.1
• NCBI GenBank Nucleotide #: NM_148962.4
• UniProt Accession #: Q8TDS5; Q86WP7; Q8NGW4
• Molecular Weight: 45,811 Da
• NCBI Official Full Name: oxoeicosanoid receptor 1
• NCBI Official Synonym Full Names: oxoeicosanoid (OXE) receptor 1
• NCBI Official Symbol: OXER1
• NCBI Official Synonym Symbols: GPCR; GPR170; TG1019
• NCBI Protein Information: oxoeicosanoid receptor 1; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019; 5-oxo-ETE G-protein coupled receptor; 5-oxo-ETE acid G-protein-coupled receptor 1
• UniProt Protein Name: Oxoeicosanoid receptor 1
• Protein Family: Oxoeicosanoid receptor
• UniProt Gene Name: OXER1
• UniProt Synonym Gene Names: GPR170; TG1019
• UniProt Entry Name: OXER1_HUMAN

Uniprot Description

OXER1: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR

Chromosomal Location of Human Ortholog: 2p21

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding; 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding

Biological Process: G-protein coupled receptor protein signaling pathway; regulation of cAMP biosynthetic process