Rabbit anti-Human Ornithine decarboxylase Polyclonal Antibody | anti-ODC1 antibody
Rabbit anti-human Ornithine decarboxylase polyclonal Antibody
Western Blot (WB)
(Western blotAll lanes: Ornithine decarboxylase antibody at 2ug/mlLane 1: EC109 whole cell lysateLane 2: 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilutionPredicted band size: 51 kDaObserved band size: 51 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embeded human colorectal carcinoma using MBS7000199 at dilution of 1:50)
Immunohistochemistry (IHC)
(Immunofluorescent analysis of HepG2 cells using MBS7000199 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]
Uniprot Description
ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]
Protein type: Cell cycle regulation; Lyase; Other Amino Acids Metabolism - glutathione; Amino Acid Metabolism - arginine and proline; EC 4.1.1.17
Chromosomal Location of Human Ortholog: 2p25
Cellular Component: cytoplasm; cytosol; perinuclear region of cytoplasm
Molecular Function: ornithine decarboxylase activity; protein binding; protein homodimerization activity
Biological Process: kidney development; polyamine metabolic process; positive regulation of cell proliferation; putrescine biosynthetic process from ornithine; regulation of amino acid metabolic process; regulation of protein catabolic process; response to virus
Disease: Colorectal Cancer
Research Articles on ODC1
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Product Notes
The ODC1 odc1 (Catalog #AAA7000199) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Ornithine decarboxylase polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ornithine decarboxylase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the ODC1 odc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ornithine decarboxylase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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