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Western Blot (WB) (Western blotAll lanes: Ornithine decarboxylase antibody at 2ug/mlLane 1: EC109 whole cell lysateLane 2: 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilutionPredicted band size: 51 kDaObserved band size: 51 kDa)

Rabbit anti-Human Ornithine decarboxylase Polyclonal Antibody | anti-ODC1 antibody

Rabbit anti-human Ornithine decarboxylase polyclonal Antibody

Gene Names
ODC1; ODC
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Ornithine decarboxylase; Polyclonal Antibody; Rabbit anti-human Ornithine decarboxylase polyclonal Antibody; ODC; ODC1; anti-ODC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Liquid
Sequence Length
461
Applicable Applications for anti-ODC1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
Immunogen
Recombinant human Ornithine decarboxylase protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21515 / sc-34181 / sc-21516 / sc-33539
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

Western Blot (WB)

(Western blotAll lanes: Ornithine decarboxylase antibody at 2ug/mlLane 1: EC109 whole cell lysateLane 2: 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilutionPredicted band size: 51 kDaObserved band size: 51 kDa)

Western Blot (WB) (Western blotAll lanes: Ornithine decarboxylase antibody at 2ug/mlLane 1: EC109 whole cell lysateLane 2: 293T whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/15000 dilutionPredicted band size: 51 kDaObserved band size: 51 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embeded human colorectal carcinoma using MBS7000199 at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embeded human colorectal carcinoma using MBS7000199 at dilution of 1:50)

Immunohistochemistry (IHC)

(Immunofluorescent analysis of HepG2 cells using MBS7000199 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunohistochemistry (IHC) (Immunofluorescent analysis of HepG2 cells using MBS7000199 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Related Product Information for anti-ODC1 antibody
L-ornithine = putrescine + CO2.Inhibited by S-nitrosylation

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.
Product Categories/Family for anti-ODC1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,148 Da
NCBI Official Full Name
ornithine decarboxylase isoform 1
NCBI Official Synonym Full Names
ornithine decarboxylase 1
NCBI Official Symbol
ODC1
NCBI Official Synonym Symbols
ODC
NCBI Protein Information
ornithine decarboxylase
UniProt Protein Name
Ornithine decarboxylase
Protein Family
UniProt Gene Name
ODC1
UniProt Synonym Gene Names
ODC
UniProt Entry Name
DCOR_HUMAN

NCBI Description

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]

Uniprot Description

ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008]

Protein type: Cell cycle regulation; Lyase; Other Amino Acids Metabolism - glutathione; Amino Acid Metabolism - arginine and proline; EC 4.1.1.17

Chromosomal Location of Human Ortholog: 2p25

Cellular Component: cytoplasm; cytosol; perinuclear region of cytoplasm

Molecular Function: ornithine decarboxylase activity; protein binding; protein homodimerization activity

Biological Process: kidney development; polyamine metabolic process; positive regulation of cell proliferation; putrescine biosynthetic process from ornithine; regulation of amino acid metabolic process; regulation of protein catabolic process; response to virus

Disease: Colorectal Cancer

Research Articles on ODC1

Similar Products

Product Notes

The ODC1 odc1 (Catalog #AAA7000199) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Ornithine decarboxylase polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ornithine decarboxylase can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Recommended dilution: WB:1:500-2000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the ODC1 odc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ornithine decarboxylase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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