Western Blot (WB)
Rabbit anti-Human, Mouse ORM1 Polyclonal Antibody | anti-ORM1 antibody
Anti-ORM1 Antibody
Gene Names
Orm1; Agp-1; Agp-2; Orm-1
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Purification
Synonyms
ORM1; Polyclonal Antibody; Anti-ORM1 Antibody; anti-ORM1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Western blot analysis of extracts of various cell lines, using ORM1 antibody. Immunohistochemistry of paraffin-embedded human kidney using ORM1 antibody at dilution of 1:200 (200x lens). Immunohistochemistry of paraffin-embedded mouse esophagus using ORM1 antibody at dilution of 1:200 (200x lens).
Purity/Purification
Affinity Purification
Form/Format
Liquid
Concentration
1mg/ml (varies by lot)
Sequence Length
207
Applicable Applications for anti-ORM1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500 - 1:2000
IHC: 1:50- 1:200
IHC: 1:50- 1:200
Immunogen
Recombinant protein of human ORM1
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Western Blot (WB)
Western Blot (WB)
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Immunohistochemistry (IHC)
Related Product Information for anti-ORM1 antibody
Alpha-1-acid glycoprotein 1 (AGP1), also called orosomucoid-1 (ORM1), is a glycoprotein synthesized mostly by hepatocytes and present in human plasma. ORM1 is an acute-phase reactant protein controlled by glucocorticoids, interleukin-1 and interleukin-6, and increase up to 5-50 times upon infection and/or inflammation. Anti-apoptotic effect and role as immunomodulator of ORM have been reported. ORM is an important carrier for synthetic drugs and influences their distribution and availability in the body. This antibody recognizes a band about 44 kDa in human plasma which may be due to the glycosylation of ORM1 or the dimer formation of the protein.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
23,895 Da
NCBI Official Full Name
Orm1
NCBI Official Synonym Full Names
orosomucoid 1
NCBI Official Symbol
Orm1
NCBI Official Synonym Symbols
Agp-1; Agp-2; Orm-1
NCBI Protein Information
alpha-1-acid glycoprotein 1
UniProt Protein Name
Alpha-1-acid glycoprotein 1
Protein Family
UniProt Gene Name
Orm1
UniProt Synonym Gene Names
Agp1; Orm-1; AGP 1; OMD 1
NCBI Description
This gene encodes a member of the lipocalin family of proteins. The encoded protein is an abundant acute-phase protein that is synthesized by hepatocytes in response to cytokines during the acute phase response. The encoded protein may regulate inflammation and metabolism. This gene is present in a gene cluster on chromosome 4. [provided by RefSeq, Aug 2015]
Uniprot Description
ORM1: Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4 B3|4 33.96 cM
Cellular Component: extracellular space
Research Articles on ORM1
Similar Products
Product Notes
The ORM1 orm1 (Catalog #AAA419823) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ORM1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ORM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500 - 1:2000 IHC: 1:50- 1:200. Researchers should empirically determine the suitability of the ORM1 orm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ORM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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