anti-Rat Orexin 1 Receptor Polyclonal Antibody | anti-HCRTR1 antibody
Anti - Orexin 1 Receptor (Hypocretin 1 Receptor) (Neat Serum)
Gene Names
HCRTR1; OX1R
Reactivity
Rat
Applications
ELISA, Western Blot
Purity
Neat serum
Synonyms
Orexin 1 Receptor; Polyclonal Antibody; Anti - Orexin 1 Receptor (Hypocretin 1 Receptor) (Neat Serum); Orexin 1 Receptor (Hypocretin 1 Receptor) (Neat Serum); anti-HCRTR1 antibody
Host
Host: Rabbit
Source: Rat
Source: Rat
Reactivity
Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Rat Orexin 1 Receptor (Hypocretin 1 Receptor) is 82% homologous with human. The appropriate control immunogenic peptides may be used to confirm specificity of antibodies. Antibody crossreactivity in various species is not established.
Purity/Purification
Neat serum
Form/Format
Serum
Supplied as neat serum with preservative.
Supplied as neat serum with preservative.
Sequence Length
425
Applicable Applications for anti-HCRTR1 antibody
ELISA, Western Blot
Application Notes
Suitable for use in ELISA, Western Blotting.
Dilution: ELISA: 1:10,000-1:1000 (Use control peptides to confirm antibody specificity)
Western Blotting: 1:1000-1:100,0 (use 50-100ng of control peptide/well; control peptides, because of their low MW (< 3kD), are not suitable for Western blot.
Dilution: ELISA: 1:10,000-1:1000 (Use control peptides to confirm antibody specificity)
Western Blotting: 1:1000-1:100,0 (use 50-100ng of control peptide/well; control peptides, because of their low MW (< 3kD), are not suitable for Western blot.
Immunogen
Synthetic peptides, 16 aa, near the N-terminus of rat Orexin 1 Receptor (Hypocretin 1 Receptor) and a 16 aa peptide near the C-terminus of human.
Preparation and Storage
-20 degree C
Related Product Information for anti-HCRTR1 antibody
Several peptides associated with feeding behavior have been reported recently. Orexins (Orexin A and Orexin B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus and are derived from the same precursor (Prepro-orexin) by proteolytic cleavage. Prepro-orexin is 130 amino acid long peptide with a putative 33 AA secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis. These neuropeptides bind and activate two closely related Orexin receptors—G-protein coupled receptors (GPCRs). Rat and human Orexin 1Receptor (Hypocretin 1 Receptor) are 416 aa, and 425aa, respectively.
Product Categories/Family for anti-HCRTR1 antibody
References
• 1. Sakurai, T. et al. (1998) Cell, 92, 573-585
• 2. DeLecca L et al (1998) PNAS 95, 322-327
• 2. DeLecca L et al (1998) PNAS 95, 322-327
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,536 Da
NCBI Official Full Name
orexin receptor type 1
NCBI Official Synonym Full Names
hypocretin (orexin) receptor 1
NCBI Official Symbol
HCRTR1
NCBI Official Synonym Symbols
OX1R
NCBI Protein Information
orexin receptor type 1; ox1-R; ox-1-R; orexin receptor 1; orexin receptor-1; OTTHUMP00000003951; OTTHUMP00000003952; hypocretin receptor 1; hypocretin receptor-1; hypocretin receptor type 1
UniProt Protein Name
Orexin receptor type 1
Protein Family
UniProt Gene Name
HCRTR1
UniProt Entry Name
OX1R_HUMAN
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Product Notes
The HCRTR1 hcrtr1 (Catalog #AAA619433) is an Antibody produced from Host: Rabbit Source: Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti - Orexin 1 Receptor (Hypocretin 1 Receptor) (Neat Serum) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Orexin 1 Receptor can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in ELISA, Western Blotting. Dilution: ELISA: 1:10,000-1:1000 (Use control peptides to confirm antibody specificity) Western Blotting: 1:1000-1:100,0 (use 50-100ng of control peptide/well; control peptides, because of their low MW (< 3kD), are not suitable for Western blot. Researchers should empirically determine the suitability of the HCRTR1 hcrtr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Orexin 1 Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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