Rabbit anti-Human OR4D6 Polyclonal Antibody | anti-OR4D6 antibody

OR4D6, CT (OR4D6, Olfactory receptor 4D6, Olfactory receptor OR11-250) (FITC)

Cat. Num. AAA6328715

• Gene Names: OR4D6; OR11-250
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OR4D6; Polyclonal Antibody; CT (OR4D6; Olfactory receptor 4D6; Olfactory receptor OR11-250) (FITC); Olfactory receptor OR11-250; anti-OR4D6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-OR4D6 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: OR4D6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-312 amino acids from the C-terminal region of human OR4D6.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(OR4D6 Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the OR4D6 antibody detected the OR4D6 protein (arrow).)

Related Product Information for anti-OR4D6 antibody

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Product Categories/Family for anti-OR4D6 antibody

Antibodies; Receptors; Olfactory

References

Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004). Fuchs, T., et al. Genomics 80(3):295-302(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 52317245
• NCBI GeneID: 219983
• NCBI Accession #: NP_001004708.1
• NCBI GenBank Nucleotide #: NM_001004708.1
• UniProt Accession #: Q8NGJ1; Q6IFF5; Q96R74; B2RNP7
• Molecular Weight: 35,954 Da
• NCBI Official Full Name: olfactory receptor 4D6
• NCBI Official Synonym Full Names: olfactory receptor, family 4, subfamily D, member 6
• NCBI Official Symbol: OR4D6
• NCBI Official Synonym Symbols: OR11-250
• NCBI Protein Information: olfactory receptor 4D6; olfactory receptor OR11-250
• UniProt Protein Name: Olfactory receptor 4D6
• Protein Family: Olfactory receptor
• UniProt Gene Name: OR4D6
• UniProt Entry Name: OR4D6_HUMAN

NCBI Description

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Uniprot Description

OR4D6: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; transmembrane receptor activity; olfactory receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception; detection of chemical stimulus involved in sensory perception of smell