Rabbit anti-Human OR2A4 Polyclonal Antibody | anti-OR2A4 antibody

OR2A4, NT (OR2A4, OR2A10, Olfactory receptor 2A4, Olfactory receptor 2A10, Olfactory receptor OR6-37) (APC)

Cat. Num. AAA6328284

• Gene Names: OR2A4; OR2A10
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OR2A4; Polyclonal Antibody; NT (OR2A4; OR2A10; Olfactory receptor 2A4; Olfactory receptor 2A10; Olfactory receptor OR6-37) (APC); Olfactory receptor OR6-37; anti-OR2A4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-OR2A4 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: OR2A4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-96 amino acids from the N-terminal region of human OR2A4.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(OR2A4 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the OR2A4 antibody detected the OR2A4 protein (arrow).)

Related Product Information for anti-OR2A4 antibody

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Product Categories/Family for anti-OR2A4 antibody

Antibodies; Receptors; Olfactory

References

Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004). Mungall, A.J., et al. Nature 425(6960):805-811(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 13929212
• NCBI GeneID: 79541
• NCBI Accession #: NP_112170.1
• NCBI GenBank Nucleotide #: NM_030908.2
• UniProt Accession #: O95047; Q0VAR3; Q6IF18; Q9NQN0
• Molecular Weight: 34,802 Da
• NCBI Official Full Name: olfactory receptor 2A4
• NCBI Official Synonym Full Names: olfactory receptor, family 2, subfamily A, member 4
• NCBI Official Symbol: OR2A4
• NCBI Official Synonym Symbols: OR2A10
• NCBI Protein Information: olfactory receptor 2A4; olfactory receptor 2A10; olfactory receptor OR6-37; olfactory receptor, family 2, subfamily A, member 10
• UniProt Protein Name: Olfactory receptor 2A4
• Protein Family: Olfactory receptor
• UniProt Gene Name: OR2A4
• UniProt Synonym Gene Names: OR2A10
• UniProt Entry Name: OR2A4_HUMAN

NCBI Description

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Uniprot Description

OR2A4: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 6q23

Cellular Component: recycling endosome; integral to membrane; plasma membrane; cleavage furrow

Molecular Function: olfactory receptor activity; taste receptor activity

Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; regulation of actin cytoskeleton organization and biogenesis; detection of chemical stimulus involved in sensory perception of smell; detection of chemical stimulus involved in sensory perception of taste