Rabbit anti-Human OR14J1 Polyclonal Antibody | anti-OR14J1 antibody

OR14J1, CT (OR14J1, OR5U1, Olfactory receptor 14J1, Hs6M1-28, Olfactory receptor 5U1, Olfactory receptor OR6-25) (Biotin)

Cat. Num. AAA6328142

• Gene Names: OR14J1; OR5U1; OR6-25; hs6M1-28; bA150A6.4
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OR14J1; Polyclonal Antibody; CT (OR14J1; OR5U1; Olfactory receptor 14J1; Hs6M1-28; Olfactory receptor 5U1; Olfactory receptor OR6-25) (Biotin); Olfactory receptor OR6-25; anti-OR14J1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

• Applicable Applications for anti-OR14J1 antibody: Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
• Application Notes: IHC: 1:10-50; ELISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: OR14J1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the C-terminal region of human OR14J1.
• Conjugate: Biotin
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(OR14J1 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the OR14J1 antibody detected the OR14J1 protein (arrow).)

Immunohistochemistry (IHC)

(OR14J1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OR14J1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-OR14J1 antibody

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Product Categories/Family for anti-OR14J1 antibody

Antibodies; Receptors; Olfactory

References

Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009): Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004). Mungall, A.J., et al. Nature 425(6960):805-811(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 53850574
• NCBI GeneID: 442191
• NCBI Accession #: NP_112208.1
• NCBI GenBank Nucleotide #: NM_030946.1
• UniProt Accession #: Q9UGF5; Q5ST27; A2BEC2; B0V078
• Molecular Weight: 35,892 Da
• NCBI Official Full Name: olfactory receptor 14J1
• NCBI Official Synonym Full Names: olfactory receptor, family 14, subfamily J, member 1
• NCBI Official Symbol: OR14J1
• NCBI Official Synonym Symbols: OR5U1; OR6-25; hs6M1-28; bA150A6.4
• NCBI Protein Information: olfactory receptor 14J1; olfactory receptor 5U1; olfactory receptor OR6-25; olfactory receptor, family 5, subfamily U member 1; olfactory receptor, family 5, subfamily U, member 1
• UniProt Protein Name: Olfactory receptor 14J1
• Protein Family: Olfactory receptor
• UniProt Gene Name: OR14J1
• UniProt Synonym Gene Names: OR5U1
• UniProt Entry Name: O14J1_HUMAN

NCBI Description

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Uniprot Description

OR14J1: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p22.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; olfactory receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell