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Immunohistochemistry (IHC) (Anti-OPN5 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit OPN5 Polyclonal Antibody | anti-OPN5 antibody

Rabbit Polyclonal to Human OPN5

Gene Names
OPN5; PGR12; GPR136; GRP136; TMEM13
Reactivity
Bat, Gibbon, Bovine, Dog, Horse, Human, Monkey, Mouse, Rabbit
Predicted Reactivity: Gorilla, Rat (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
OPN5; Polyclonal Antibody; Rabbit Polyclonal to Human OPN5; Anti-OPN5 Antibody (Transmembrane Domain) IHC-plus; G-protein coupled receptor 136; Neuropsin; Opsin 5; Opsin-5; PGR12; TMEM13; Transmembrane protein 13; DJ402H5.1; GPR136; Human OPN5; anti-OPN5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Bat, Gibbon, Bovine, Dog, Horse, Human, Monkey, Mouse, Rabbit
Predicted Reactivity: Gorilla, Rat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human OPN5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
354
Applicable Applications for anti-OPN5 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (30 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from 7th transmembrane domain of human OPN5. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Dog, Bat, Bovine, Elephant, Panda, Horse, Rabbit (100%); Gorilla, Rat (94%).
Immunogen Type
Synthetic peptide
Immunogen
OPN5 antibody was raised against synthetic 17 amino acid peptide from 7th transmembrane domain of human OPN5. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Dog, Bat, Bovine, Elephant, Panda, Horse, Rabbit (100%); Gorilla, Rat (94%); Platypus (88%); Opossum, Turkey, Sparrow, Chicken (82%).
Antigen Modification
Transmembrane Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-OPN5 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-OPN5 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-OPN5 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-OPN5 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-OPN5 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-OPN5 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-OPN5 antibody
GPR136 is an Orphan-A GPCR with an unknown ligand.
Product Categories/Family for anti-OPN5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,727 Da
NCBI Official Full Name
opsin-5
NCBI Official Synonym Full Names
opsin 5
NCBI Official Symbol
OPN5
NCBI Official Synonym Symbols
PGR12; GPR136; GRP136; TMEM13
NCBI Protein Information
opsin-5; neuropsin; transmembrane protein 13; G-protein coupled receptor 136
UniProt Protein Name
Opsin-5
Protein Family
UniProt Gene Name
OPN5
UniProt Synonym Gene Names
GPR136; PGR12; TMEM13
UniProt Entry Name
OPN5_HUMAN

NCBI Description

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Uniprot Description

neuropsin: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This opsin gene is expressed in the eye, brain, testes, and spinal cord. This gene belongs to the seven-exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven-exon opsin genes, this family member may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 6p12.3

Cellular Component: integral to membrane

Molecular Function: G-protein coupled receptor activity; 11-cis retinal binding; photoreceptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; visual perception; phototransduction; protein-chromophore linkage

Research Articles on OPN5

Similar Products

Product Notes

The OPN5 opn5 (Catalog #AAA243439) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human OPN5 reacts with Bat, Gibbon, Bovine, Dog, Horse, Human, Monkey, Mouse, Rabbit Predicted Reactivity: Gorilla, Rat (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's OPN5 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (30 ug/ml). Researchers should empirically determine the suitability of the OPN5 opn5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OPN5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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