anti-Mouse OGG1 Polyclonal Antibody | anti-OGG1 antibody
Anti - OGG1 (8-Oxoguanine DNA Glycosylase)
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Serum
Synonyms
OGG1; Polyclonal Antibody; Anti - OGG1 (8-Oxoguanine DNA Glycosylase); OGG1 (8-Oxoguanine DNA Glycosylase); anti-OGG1 antibody
Host
Host: Rabbit
Source: Mouse
Source: Mouse
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse OGG1. The peptide sequence has 83% homology with rat OGG1 (1); no significant sequence homology exists with hOGG1. We recommend the use of anti-human OGG1 for detecting hOGG1
Purity/Purification
Serum
Form/Format
Serum
Supplied as a liquid in PBS, containing 40% glycerol and 0.05% sodium azide.
Supplied as a liquid in PBS, containing 40% glycerol and 0.05% sodium azide.
Applicable Applications for anti-OGG1 antibody
ELISA, Western Blot
Application Notes
Suitable for use in ELISA and Western Blot. Other applications not tested.
Dilution: ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well.
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Dilution: ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well.
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Immunogen
An 18 aa peptide close to the N-terminus of mouse OGG1 (KLH coupled)
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-OGG1 antibody
Mouse 8-Oxoguanine DNA Glycosylase 1 (mOGG1; 345 aa) is involved in the excision of 7, 8-dihydro-8-oxoguanine produced as a result of DNA damage. This gene has been localized on human chromosome 3p25. Several forms of hOGG protein have been cloned differing in lengths (351-424 aa) (refs 1). 8-Oxoguanine- DNA glyosylase (OGG1) is a DNA repair protein that is primarily responsible for the repair of 8-oxoguanine (8-oxo-G). It possesses both DNA glycosylase and AP (apurinic) lyase activity and is a functional analog of the bacteria Fpg protein. OGG1 releases 8- oxoguanine (8-oxo-G) from mutated DNA and nicks the DNA strand. Although its glycosidase activity is very efficient, its lyase activity is weak and is highest for substrates having a C as the opposite base. OGG1 is a b-lyase generating an -unsaturated sugar moiety at the 3'-terminus. Murine OGG1 is a 345 amino acid protein of 38.8 kDa. It displays 84% identity to the human OGG1.
Product Categories/Family for anti-OGG1 antibody
References
• 1. Yoshinari T et al (1997) Gene Accession # U88621; Aburatani H et al (1997) gene accession # U88620; Radicella JP et al (1997) PNAS 94, 8010-8015; Rosenquist TA et al (1997) PNAS 94, 7429-7434
• 2. Kuo FC et al (1997) J Exp Med.
• 3. Tani M et al (1997) gene accession # AF012912; Prieto-Alamo MJ et al (1997) gene accession # AF029690
• 2. Kuo FC et al (1997) J Exp Med.
• 3. Tani M et al (1997) gene accession # AF012912; Prieto-Alamo MJ et al (1997) gene accession # AF029690
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Product Notes
The OGG1 (Catalog #AAA613553) is an Antibody produced from Host: Rabbit Source: Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti - OGG1 (8-Oxoguanine DNA Glycosylase) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's OGG1 can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in ELISA and Western Blot. Other applications not tested. Dilution: ELISA: 1:10,000-1:50,000 using 50-100 ng control peptide per well. Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the OGG1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OGG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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