Rabbit anti-Human OCA2 Polyclonal Antibody | anti-OCA2 antibody

OCA2, NT (OCA2, D15S12, P, P protein, Melanocyte-specific transporter protein, Pink-eyed dilution protein homolog) (Azide free) (HRP)

Cat. Num. AAA6327528

• Gene Names: OCA2; P; BEY; PED; BEY1; BEY2; BOCA; EYCL; HCL3; EYCL2; EYCL3; SHEP1; D15S12
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OCA2; Polyclonal Antibody; NT (OCA2; D15S12; P; P protein; Melanocyte-specific transporter protein; Pink-eyed dilution protein homolog) (Azide free) (HRP); Pink-eyed dilution protein homolog; anti-OCA2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-OCA2 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: OCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the N-terminal region of human OCA2.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(OCA2 Antibody (N-Term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the OCA2 antibody detected the OCA2 protein (arrow).)

Related Product Information for anti-OCA2 antibody

This gene encodes the human homologue of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine-a precursor of melanin. Mutations in this gene result in type 2 oculocutaneous albinism. [provided by RefSeq].

Product Categories/Family for anti-OCA2 antibody

Antibodies; Transport Proteins

References

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Mengel-From, J., et al. Forensic Sci Int Genet 4(5):323-328(2010). Ibarrola-Villava, M., et al. Exp. Dermatol. 19(9):836-844(2010). Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010).

NCBI and Uniprot Product Information

• NCBI GI #: 157266326
• NCBI GeneID: 4948
• NCBI Accession #: NP_000266.2
• NCBI GenBank Nucleotide #: NM_000275.2
• UniProt Accession #: Q04671; Q15211; Q15212; Q96EN1; Q9UMI5
• Molecular Weight: 92,850 Da
• NCBI Official Full Name: P protein isoform 1
• NCBI Official Synonym Full Names: oculocutaneous albinism II
• NCBI Official Symbol: OCA2
• NCBI Official Synonym Symbols: P; BEY; PED; BEY1; BEY2; BOCA; EYCL; HCL3; EYCL2; EYCL3; SHEP1; D15S12
• NCBI Protein Information: P protein; eye color 3 (brown); hair color 3 (brown); eye color 2 (central brown); total brown iris pigmentation; pink-eyed dilution protein homolog; melanocyte-specific transporter protein; oculocutaneous albinism II (pink-eye dilution homolog, mouse)
• UniProt Protein Name: P protein
• Protein Family: P protein
• UniProt Gene Name: OCA2
• UniProt Synonym Gene Names: D15S12; P
• UniProt Entry Name: P_HUMAN