Rabbit NUTF2 Polyclonal Antibody | anti-NUTF2 antibody

NUTF2 Polyclonal Antibody

Cat. Num. AAA2562704

• Gene Names: NUTF2; NTF2; PP15; NTF-2
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: NUTF2; Polyclonal Antibody; NUTF2 Polyclonal Antibody; NTF2; Nuclear transport factor 2; NTF-2; Placental protein 15; PP15; anti-NUTF2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 1.2mg/mL (varies by lot)
• Sequence Length: 127

• Applicable Applications for anti-NUTF2 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500-1:2000; ELISA: 1:5000-1:10000
• Immunogen: Fusion protein of human NUTF2
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Mouse heart tissue lysate using NUTF2 Polyclonal Antibody at dilution of 1:1000)

Related Product Information for anti-NUTF2 antibody

NUTF2 (nuclear transport factor 2), also named as NTF2, is a cytosolic protein responsible for nuclear import of Ran, a small Ras-like GTPase involved in a number of critical cellular processes, including cell cycle regulation, chromatin organization during mitosis, reformation of the nuclear envelope following mitosis, and controlling the directionality of nucleocytoplasmic transport. Nucleocytoplasmic translocation of NTF2 is regulated in mammalian cells, and may involve a tyrosine and/or threonine kinase-dependent signal transduction mechanism(s). The MW of this protein is 14 kDa, and this antibody specially recognises the 14 kDa protein.

NCBI and Uniprot Product Information

• NCBI GI #: 5031985
• NCBI GeneID: 10204
• NCBI Accession #: NP_005787.1; BC002348
• NCBI GenBank Nucleotide #: NP_005787.1
• UniProt Accession #: P61970
• Molecular Weight: 14 kDa
• NCBI Official Full Name: nuclear transport factor 2
• NCBI Official Synonym Full Names: nuclear transport factor 2
• NCBI Official Symbol: NUTF2
• NCBI Official Synonym Symbols: NTF2; PP15; NTF-2
• NCBI Protein Information: nuclear transport factor 2
• UniProt Protein Name: Nuclear transport factor 2
• UniProt Gene Name: NUTF2
• UniProt Synonym Gene Names: NTF2; NTF-2; PP15
• UniProt Entry Name: NTF2_HUMAN

NCBI Description

This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016]

Uniprot Description

NUTF2: Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import. Homodimer.

Protein type: Nuclear import

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: nuclear pore; cytosol

Molecular Function: protein binding; transporter activity

Biological Process: protein export from nucleus