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Rabbit anti-Human NUP98 Polyclonal Antibody | anti-NUP98 antibody

NUP98 Conjugated Antibody

Gene Names
NUP98; ADIR2; NUP96; NUP196
Reactivity
Human
Applications
Most Applications
Synonyms
NUP98; Polyclonal Antibody; NUP98 Conjugated Antibody; ADIR2; NUP96; NUP196; anti-NUP98 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total NUP98 protein.
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-NUP98 antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
Synthetic peptide of human nucleoporin 98kDa
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
Related Product Information for anti-NUP98 antibody
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
186,268 Da
NCBI Official Full Name
nuclear pore complex protein Nup98-Nup96 isoform 3
NCBI Official Synonym Full Names
nucleoporin 98kDa
NCBI Official Symbol
NUP98
NCBI Official Synonym Symbols
ADIR2; NUP96; NUP196
NCBI Protein Information
nuclear pore complex protein Nup98-Nup96; GLFG-repeat containing nucleoporin; nucleoporin 98kD
UniProt Protein Name
Nuclear pore complex protein Nup98-Nup96
UniProt Gene Name
NUP98
UniProt Synonym Gene Names
ADAR2; Nup98; Nup96
UniProt Entry Name
NUP98_HUMAN

Uniprot Description

NUP98: Nup98 and Nup96 play a role in the bidirectional transport across the nucleoporin complex (NPC). The repeat domain in Nup98 has a direct role in the transport. Nup98 interacts directly with Nup96. Nup96 is part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus. May interact with RAE1. Interacts with vesicular stomatitis virus protein M. Belongs to the nucleoporin GLFG family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Nucleoporin

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: nucleoplasm; kinetochore; nuclear membrane; nuclear pore; nuclear envelope; cytosol; nuclear inclusion body

Molecular Function: protein binding; structural constituent of nuclear pore; transporter activity; peptide binding

Biological Process: nuclear pore complex assembly; mRNA transport; viral reproduction; cytokine and chemokine mediated signaling pathway; protein import into nucleus, docking; mitotic nuclear envelope disassembly; nucleocytoplasmic transport; pathogenesis; glucose transport; viral infectious cycle; nuclear pore organization and biogenesis; hexose transport; carbohydrate metabolic process; gene expression; viral transcription; mitotic cell cycle; DNA replication; transmembrane transport

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Product Notes

The NUP98 nup98 (Catalog #AAA9449463) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NUP98 Conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NUP98 can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the NUP98 nup98 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NUP98, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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