Rabbit NUP93 Polyclonal Antibody | anti-NUP93 antibody

NUP93 Antibody (N-Term)

Cat. Num. AAA9217218

• Gene Names: NUP93; NIC96; NPHS12
• Reactivity: Human, Mouse; Predicted Reactivity: Bovine, Mouse, Rat
• Applications: Western Blot, ELISA
• Synonyms: NUP93; Polyclonal Antibody; NUP93 Antibody (N-Term); Nuclear pore complex protein Nup93; 93 kDa nucleoporin; Nucleoporin Nup93; KIAA0095; anti-NUP93 antibody

• Host: Rabbit
• Reactivity: Human, Mouse; Predicted Reactivity: Bovine, Mouse, Rat
• Clonality: Polyclonal
• Isotype: Ig
• Specificity: This NUP93 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 20-54 amino acids from the human NUP93.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Sequence Length: 696

• Applicable Applications for anti-NUP93 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB:~~1:2000
• Subtitle: Purified Rabbit Polyclonal Antibody (Pab)
• Cellular Location: Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore.
• Antigen Type: Synthesized Peptide
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-NUP93 Antibody (N-Term) at 1:2000 dilutionLane 1: F9 whole cell lysateLane 2: Jurkat whole cell lysateLane 3: K562 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 93 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Related Product Information for anti-NUP93 antibody

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC.

Product Categories/Family for anti-NUP93 antibody

Primary Antibodies; Signal Transduction

References

Nagase T.,et al.DNA Res. 2:37-43 (1995). Ota T.,et al.Nat. Genet. 36:40-45 (2004). Martin J.,et al.Nature 432:988-994 (2004). Grandi P.,et al.Mol. Biol. Cell 8:2017-2038 (1997). Hase M.E.,et al.Mol. Biol. Cell 14:1923-1940 (2003).

NCBI and Uniprot Product Information

• NCBI GI #: 338753429
• NCBI GeneID: 9688
• NCBI Accession #: NP_001229724.1
• NCBI GenBank Nucleotide #: NM_001242795.1
• UniProt Accession #: Q8N1F7; Q14705; B3KPQ8
• Molecular Weight: 93488 Da
• NCBI Official Full Name: nuclear pore complex protein Nup93 isoform 2
• NCBI Official Synonym Full Names: nucleoporin 93kDa
• NCBI Official Symbol: NUP93
• NCBI Official Synonym Symbols: NIC96; NPHS12
• NCBI Protein Information: nuclear pore complex protein Nup93
• UniProt Protein Name: Nuclear pore complex protein Nup93
• Protein Family: Nuclear pore complex protein
• UniProt Gene Name: NUP93
• UniProt Synonym Gene Names: KIAA0095
• UniProt Entry Name: NUP93_HUMAN

Uniprot Description

NUP93: a nuclear pore protein (nucleoporin) required for correct nuclear pore assembly. The nuclear pore complex, comprised of approximately 30 nucleoporins, mediates the exchange of macromolecules across the nuclear envelope. It is comprised of approximately 30 proteins termed nucleoporins that are each present in multiple copies. Belongs to the nucleoporin interacting component (NIC) family.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: membrane; nuclear envelope; nuclear membrane; nuclear pore

Molecular Function: structural constituent of nuclear pore

Biological Process: mitotic nuclear envelope disassembly; mRNA export from nucleus; nuclear pore complex assembly; poly(A)+ mRNA export from nucleus; positive regulation of defense response to virus by host; protein import into nucleus; protein sumoylation; RNA-mediated gene silencing; tRNA export from nucleus; viral reproduction; viral transcription