Rabbit anti-Human NUP54 Polyclonal Antibody | anti-Nup54 antibody

NUP54 (Nucleoporin p54, 54kD Nucleoporin, MGC13407)

Cat. Num. AAA6012712

• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: NUP54; Polyclonal Antibody; NUP54 (Nucleoporin p54; 54kD Nucleoporin; MGC13407); Anti -NUP54 (Nucleoporin p54; anti-Nup54 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human NUP54.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSCMPSNKDEDGLVVLVFNKKETEIRSQQQQLVESLHKVLGGNQTLTVNVEGTKTLPDDQTEVVIYVVERSPNGTSRRVPATTLYAHFEQANIKTQLQQLGVTLSMTRTELSPAQIKQLLQNPPAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISELQKNQTTSVAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQGELNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISIIKDDLEDIKLVEHGLNETIHIRGGVFS

• Applicable Applications for anti-Nup54 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human NUP54, aa1-507 (NP_059122.2).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of NUP54 expression in transfected 293T cell line by NUP54 polyclonal antibody. Lane 1: NUP54 transfected lysate (55.4kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-Nup54 antibody

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. NUP54 is a member of the phe-gly (FG) repeat-containing nucleoporin subset.

Product Categories/Family for anti-Nup54 antibody

Antibodies; Abs to Nuclear Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 8393855
• NCBI GeneID: 53372
• NCBI Accession #: NP_059057.1
• NCBI GenBank Nucleotide #: NM_017361.1
• UniProt Accession #: P70582
• Molecular Weight: 55,745 Da
• NCBI Official Full Name: nuclear pore complex protein Nup54
• NCBI Official Synonym Full Names: nucleoporin 54
• NCBI Official Symbol: Nup54
• NCBI Protein Information: nuclear pore complex protein Nup54; nucleoporin p54; nucleoporin Nup54; 54 kDa nucleoporin
• UniProt Protein Name: Nuclear pore complex protein Nup54
• Protein Family: Nucleoporin
• UniProt Gene Name: Nup54
• UniProt Entry Name: NUP54_RAT

NCBI Description

a component of the nuclear pore complex and may be involved in nuclear protein import [RGD, Feb 2006]

Uniprot Description

Function: Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. Ref.1

Subunit structure: Component of the p62 complex, a complex composed of NUP62, NUP54, and the isoform p58 and isoform p45 of NUPL1. Ref.1

Subcellular location: Nucleus › nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note: Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter. Ref.1

Domain: Contains FG repeats.

Post-translational modification: O-glycosylated.

Sequence similarities: Belongs to the NUP54 family.