Rabbit Nup160 Polyclonal Antibody | anti-Nup160 antibody

Nup160 (L424) Polyclonal Antibody

Cat. Num. AAA3003669

• Gene Names: NUP160; NPHS19
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: Nup160; Polyclonal Antibody; Nup160 (L424) Polyclonal Antibody; Nuclear pore complex protein Nup160; 160 kDa nucleoporin; Nucleoporin Nup160; NUP160; KIAA0197; NUP120; anti-Nup160 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Nup160 (L424) polyclonal antibody detects endogenous levels of Nup160 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 1436

• Applicable Applications for anti-Nup160 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic peptide, corresponding to amino acids 400-450 of Human Nup160.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of Nup160 (L424) pAb at 1:2000 dilutionLane1:Hela whole cell lysate (20ug) Lane2:K562 whole cell lysate (20ug) Lane3:The Testis tissue lysate of Mouse (40ug) Lane4:The Uterus tissue lysate of Rat (40ug))

Related Product Information for anti-Nup160 antibody

Nuclear pore complexes (NPCs) are the channels for the bi-directional movement of macromolecules between the nucleus and cytoplasm, and contain more than 100 different subunits. Many of them belong to a family called nucleoporins, which are characterized by the presence of O-linked N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG).Nuclear pore complex protein Nup96 (Nup96) is formed by cleavage of a 186 kDa precursor protein. This proteolytic cleavage yields two nucleoporins, Nup98 and Nup96. Nup96 is part of the Nup160 subcomplex in the nuclear pore (which consists of Nup160, Nup133, Nup107 and Nup96). Nup96 plays a major role in the two-way transport across the nuclear pore and is important in RNA export.

NCBI and Uniprot Product Information

• NCBI GI #: 54859722
• NCBI GeneID: 23279
• NCBI Accession #: NP_056046.1
• NCBI GenBank Nucleotide #: NP_056046.1
• UniProt Accession #: Q12769
• Molecular Weight: ~150kDa
• NCBI Official Full Name: nuclear pore complex protein Nup160 isoform 1
• NCBI Official Synonym Full Names: nucleoporin 160
• NCBI Official Symbol: NUP160
• NCBI Official Synonym Symbols: NPHS19
• NCBI Protein Information: nuclear pore complex protein Nup160
• UniProt Protein Name: Nuclear pore complex protein Nup160
• Protein Family: Nuclear pore complex protein
• UniProt Gene Name: NUP160
• UniProt Synonym Gene Names: KIAA0197; NUP120
• UniProt Entry Name: NU160_HUMAN

NCBI Description

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004]

Uniprot Description

NUP160: Involved in poly(A)+ RNA transport. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: kinetochore; nuclear envelope; nuclear pore; cytosol

Molecular Function: protein binding; nucleocytoplasmic transporter activity

Biological Process: viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; viral infectious cycle; glucose transport; mRNA export from nucleus; protein transport; hexose transport; carbohydrate metabolic process; viral transcription; gene expression; mitotic cell cycle; transmembrane transport