Rabbit anti-Mouse NUP160 Polyclonal Antibody | anti-NUP160 antibody

NUP160, ID (NUP160, KIAA0197, NUP120, Nuclear pore complex protein Nup160, 160kD nucleoporin, Nucleoporin Nup160) (FITC)

Cat. Num. AAA6327252

• Reactivity: Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: NUP160; Polyclonal Antibody; ID (NUP160; KIAA0197; NUP120; Nuclear pore complex protein Nup160; 160kD nucleoporin; Nucleoporin Nup160) (FITC); Nucleoporin Nup160; anti-NUP160 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-NUP160 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:50-100; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: NUP160 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-429 amino acids from the Central region of human NUP160.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(NUP160 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the NUP160 antibody detected the NUP160 protein (arrow).)

Immunohistochemistry (IHC)

(NUP160 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NUP160 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-NUP160 antibody

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.

Product Categories/Family for anti-NUP160 antibody

Antibodies; KIAA; orf

References

Mishra, R.K., et al. Nat. Cell Biol. 12(2):164-169(2010). Platani, M., et al. Mol. Biol. Cell 20(24):5260-5275(2009). Leksa, N.C., et al. Structure 17(8):1082-1091(2009). Zuccolo, M., et al. EMBO J. 26(7):1853-1864(2007). Glavy, J.S., et al. Proc. Natl. Acad. Sci. U.S.A. 104(10):3811-3816(2007).

NCBI and Uniprot Product Information

• NCBI GI #: 54859722
• NCBI GeneID: 23279
• NCBI Accession #: NP_056046.1
• NCBI GenBank Nucleotide #: NM_015231.1
• UniProt Accession #: Q12769; Q08AD3; Q7Z5X6; Q96GB3; Q9H660; B4DYE8; B4E2J9
• Molecular Weight: 162,121 Da
• NCBI Official Full Name: nuclear pore complex protein Nup160
• NCBI Official Synonym Full Names: nucleoporin 160kDa
• NCBI Official Symbol: NUP160
• NCBI Protein Information: nuclear pore complex protein Nup160; nucleoporin Nup160; 160 kDa nucleoporin
• UniProt Protein Name: Nuclear pore complex protein Nup160
• Protein Family: Nuclear pore complex protein
• UniProt Gene Name: NUP160
• UniProt Synonym Gene Names: KIAA0197; NUP120
• UniProt Entry Name: NU160_HUMAN

NCBI Description

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004]

Uniprot Description

NUP160: Involved in poly(A)+ RNA transport. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 11p11.2

Cellular Component: kinetochore; nuclear envelope; nuclear pore; cytosol

Molecular Function: protein binding; nucleocytoplasmic transporter activity

Biological Process: viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; viral infectious cycle; glucose transport; mRNA export from nucleus; protein transport; hexose transport; carbohydrate metabolic process; viral transcription; gene expression; mitotic cell cycle; transmembrane transport