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Immunohistochemistry (IHC) (DAB staining on fromalin fixed paraffin- embedded prostate gland tissue))

Rabbit anti-Human Nucleoporin 37kDa Polyclonal Antibody | anti-NUP37 antibody

Nucleoporin 37kDa (NUP37) Polyclonal Antibody

Gene Names
NUP37; p37
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Nucleoporin 37kDa; Polyclonal Antibody; Nucleoporin 37kDa (NUP37) Polyclonal Antibody; p37; Nup107-160 subcomplex subunit Nup37; anti-NUP37 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against NUP37. It has been selected for its ability to recognize NUP37 in immunohistochemical staining and western blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Supplied as solution form in PBS, pH7.4 containing 0.02% NaN3, 50% glycerol.
Concentration
500ug/mL (varies by lot)
Sequence Length
326
Applicable Applications for anti-NUP37 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western Blot: 1:50-400
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200
Immunoglobulin Type
IgG
Conjugate
No Conjugate
Cross Reactivity
Human
Organism Species
Human
Fragment
NUP37 (Asn34~Gln279)
Quality Control
Content: The quality control contains recombinant NUP37 (Asn34~Gln279) disposed in loading buffer.
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control.Not used for other purposes.
Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2051451
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC)

(DAB staining on fromalin fixed paraffin- embedded prostate gland tissue))

Immunohistochemistry (IHC) (DAB staining on fromalin fixed paraffin- embedded prostate gland tissue))

Immunohistochemistry (IHC)

(DAB staining on IHC-P; Samples: Human Breast cancer Tissue)

Immunohistochemistry (IHC) (DAB staining on IHC-P; Samples: Human Breast cancer Tissue)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,708 Da
NCBI Official Full Name
nucleoporin Nup37
NCBI Official Synonym Full Names
nucleoporin 37
NCBI Official Symbol
NUP37
NCBI Official Synonym Symbols
p37
NCBI Protein Information
nucleoporin Nup37
UniProt Protein Name
Nucleoporin Nup37
Protein Family
UniProt Gene Name
NUP37
UniProt Synonym Gene Names
p37

NCBI Description

Nuclear pore complexes (NPCs) are used for transporting macromolecules between the cytoplasm and the nucleus. NPCs consist of multiple copies of 30 distinct proteins (nucleoporins), which assemble into biochemically-separable subcomplexes. The protein encoded by this gene is part of a subcomplex (Nup107-160) that is required for proper NPC function as well as for normal kinetochore-microtubule interaction and mitosis. [provided by RefSeq, Dec 2015]

Uniprot Description

NUP37: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 12q23.2

Cellular Component: cytosol; kinetochore; nuclear envelope; nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: cell division; mitotic nuclear envelope disassembly; mRNA export from nucleus; protein sumoylation; regulation of glycolysis; sister chromatid cohesion; tRNA export from nucleus; viral process; viral transcription

Research Articles on NUP37

Similar Products

Product Notes

The NUP37 nup37 (Catalog #AAA2032544) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Nucleoporin 37kDa (NUP37) Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Nucleoporin 37kDa can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western Blot: 1:50-400 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the NUP37 nup37 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nucleoporin 37kDa, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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