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Rabbit nuclear autoantigenic sperm protein Polyclonal Antibody | anti-Nasp antibody

Rabbit anti-human nuclear autoantigenic sperm protein (histone-binding) polyclonal Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Antigen Affinity Purified
Synonyms
nuclear autoantigenic sperm protein; Polyclonal Antibody; Rabbit anti-human nuclear autoantigenic sperm protein (histone-binding) polyclonal Antibody; nuclear autoantigenic sperm protein (histone-binding); NASP; DKFZp547F162; FLB7527; FLJ31599; FLJ35510; MGC19722; MGC20372; MGC2297; PRO1999; anti-Nasp antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
776
Applicable Applications for anti-Nasp antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Immunogen
Human NASP
Storage Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161914 / sc-161915 / sc-161916

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
84,200 Da
NCBI Official Full Name
nuclear autoantigenic sperm protein
NCBI Official Synonym Full Names
nuclear autoantigenic sperm protein (histone-binding)
NCBI Official Symbol
Nasp
NCBI Protein Information
nuclear autoantigenic sperm protein; nasp
UniProt Protein Name
Nuclear autoantigenic sperm protein
UniProt Gene Name
Nasp
UniProt Synonym Gene Names
NASP
UniProt Entry Name
NASP_RAT

Uniprot Description

NASP: Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA. Belongs to the NASP family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Cellular Component: nucleoplasm; protein complex; cytoplasm; nuclear chromatin; nucleus

Molecular Function: histone binding; Hsp90 protein binding

Biological Process: cell proliferation; protein transport; blastocyst development; DNA replication-independent nucleosome assembly; male gonad development; histone exchange; response to testosterone stimulus; DNA replication; DNA replication-dependent nucleosome assembly

Research Articles on Nasp

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Product Notes

The Nasp nasp (Catalog #AAA712153) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human nuclear autoantigenic sperm protein (histone-binding) polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's nuclear autoantigenic sperm protein can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the Nasp nasp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "nuclear autoantigenic sperm protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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