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Immunohistochemistry (IHC) (Anti-NPY5R antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit NPY5R Polyclonal Antibody | anti-NPY5R antibody

Rabbit Polyclonal to Human NPY5R

Gene Names
NPY5R; NPYR5; NPY5-R; NPYY5-R
Reactivity
Gibbon, Gorilla, Human, Monkey
Applications
Immunohistochemistry, Immunocytochemistry
Purity
Immunoaffinity Purified
Synonyms
NPY5R; Polyclonal Antibody; Rabbit Polyclonal to Human NPY5R; Anti-NPY5R Antibody (Cytoplasmic Domain) IHC-plus; NPYR5; NPY5-R; NPYY5; Neuropeptide Y receptor Y5; NPYY5-R; Neuropeptide Y receptor type 5; Neuropeptide Y5 receptor; NPY-Y5 receptor; NPY5 receptor; Y5 receptor; Human NPY5R; anti-NPY5R antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human, Monkey
Clonality
Polyclonal
Specificity
Human NPY5R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
445
Applicable Applications for anti-NPY5R antibody
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC)
Application Notes
ICC (4 - 6 ug/ml), IHC-P (4 - 8 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human NPY5R. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Bovine, Panda (88%); Dog, Rabbit, Pig (82%).
Immunogen Type
Synthetic peptide
Immunogen
NPY5R antibody was raised against synthetic 17 amino acid peptide from 3rd cytoplasmic domain of human NPY5R. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Bovine, Panda (88%); Dog, Rabbit, Pig (82%).
Antigen Modification
Cytoplasmic Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-NPY5R antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-NPY5R antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Transfection

(Anti-NPY5R antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with NPY5R.)

Transfection (Anti-NPY5R antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with NPY5R.)

Transfection Control

(Anti-NPY5R antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.)

Transfection Control (Anti-NPY5R antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.)
Related Product Information for anti-NPY5R antibody
NPY5R, a Neuropeptide Receptor GPCR, has been suggested to be the main receptor mediating NPY-induced food intake in rats.
Product Categories/Family for anti-NPY5R antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,727 Da
NCBI Official Full Name
neuropeptide Y receptor type 5
NCBI Official Synonym Full Names
neuropeptide Y receptor Y5
NCBI Official Symbol
NPY5R
NCBI Official Synonym Symbols
NPYR5; NPY5-R; NPYY5-R
NCBI Protein Information
neuropeptide Y receptor type 5; Y5 receptor; NPY-Y5 receptor
UniProt Protein Name
Neuropeptide Y receptor type 5
Protein Family
UniProt Gene Name
NPY5R
UniProt Synonym Gene Names
NPYR5; NPY5-R; NPYY5-R; Y5 receptor
UniProt Entry Name
NPY5R_HUMAN

Uniprot Description

NPY5R: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 4q31-q32

Cellular Component: neuron projection; integral to plasma membrane; cytoplasm; plasma membrane

Molecular Function: peptide YY receptor activity; pancreatic polypeptide receptor activity; neuropeptide Y receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; generation of ovulation cycle rhythm; synaptic transmission; negative regulation of glutamate secretion; eating behavior; neuropeptide signaling pathway; positive regulation of acute inflammatory response; positive regulation of smooth muscle cell proliferation; negative regulation of synaptic transmission, GABAergic; negative regulation of apoptosis

Research Articles on NPY5R

Similar Products

Product Notes

The NPY5R npy5r (Catalog #AAA244878) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human NPY5R reacts with Gibbon, Gorilla, Human, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's NPY5R can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC). ICC (4 - 6 ug/ml), IHC-P (4 - 8 ug/ml). Researchers should empirically determine the suitability of the NPY5R npy5r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPY5R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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