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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS7045135 at dilution 1:100)

Rabbit anti-Human NPTN Polyclonal Antibody | anti-NPTN antibody

NPTN Antibody

Gene Names
NPTN; GP55; GP65; SDR1; np55; np65; SDFR1
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
NPTN; Polyclonal Antibody; NPTN Antibody; Neuroplastin; Stromal cell-derived receptor 1; SDR-1; SDFR1; SDR1; anti-NPTN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
394
Applicable Applications for anti-NPTN antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
Recommended dilution: IHC: 1:20-1:200
Species
Human
Immunogen
Recombinant human Neuroplastin protein (29-200AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-131989 / sc-131990 / sc-102034
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS7045135 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS7045135 at dilution 1:100)
Related Product Information for anti-NPTN antibody
Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,931 Da
NCBI Official Full Name
neuroplastin isoform c
NCBI Official Synonym Full Names
neuroplastin
NCBI Official Symbol
NPTN
NCBI Official Synonym Symbols
GP55; GP65; SDR1; np55; np65; SDFR1
NCBI Protein Information
neuroplastin
UniProt Protein Name
Neuroplastin
Protein Family
UniProt Gene Name
NPTN
UniProt Synonym Gene Names
SDFR1; SDR1; SDR-1
UniProt Entry Name
NPTN_HUMAN

NCBI Description

This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009]

Uniprot Description

neuroplastin: Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. May also regulate neurite outgrowth by activating the FGFR1 signaling pathway. May play a role in synaptic plasticity. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q22

Cellular Component: cell surface; presynaptic membrane

Molecular Function: cell adhesion molecule binding; type 1 fibroblast growth factor receptor binding

Biological Process: elevation of cytosolic calcium ion concentration; homophilic cell adhesion; positive regulation of fibroblast growth factor receptor signaling pathway; positive regulation of long-term neuronal synaptic plasticity; positive regulation of protein amino acid phosphorylation

Research Articles on NPTN

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Product Notes

The NPTN nptn (Catalog #AAA7045135) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPTN Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NPTN can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Recommended dilution: IHC: 1:20-1:200. Researchers should empirically determine the suitability of the NPTN nptn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPTN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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