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Western Blot (WB) (Western Blot analysis of Mouse liver tissue using NPR2 Polyclonal Antibody at dilution of 1:300)

Rabbit NPR2 Polyclonal Antibody | anti-NPR2 antibody

NPR2 Polyclonal Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
NPR2; Polyclonal Antibody; NPR2 Polyclonal Antibody; AMDM; ANPb; ECDM; NPRB; ANPRB; GUC2B; NPRBi; GUCY2B; anti-NPR2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.8mg/mL (varies by lot)
Sequence Length
624
Applicable Applications for anti-NPR2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human NPR2
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western Blot analysis of Mouse liver tissue using NPR2 Polyclonal Antibody at dilution of 1:300)

Western Blot (WB) (Western Blot analysis of Mouse liver tissue using NPR2 Polyclonal Antibody at dilution of 1:300)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human ovarian cancer using NPR2 Polyclonal Antibody at dilution of 1:45)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human ovarian cancer using NPR2 Polyclonal Antibody at dilution of 1:45)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human breast cancer using NPR2 Polyclonal Antibody at dilution of 1:45)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human breast cancer using NPR2 Polyclonal Antibody at dilution of 1:45)
Related Product Information for anti-NPR2 antibody
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
69,859 Da
NCBI Official Full Name
NPR2
UniProt Protein Name
Nitrogen permease regulator 2
UniProt Gene Name
NPR2
UniProt Entry Name
NPR2_YEAST

Uniprot Description

Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis. Mediates inactivation of the TORC1 complex in response to amino acid starvation. Post-transcriptional regulator of nitrogen permeases. May be involved in putative NPR1-dependent phosphorylation of nitrogen permeases or in the processing and targeting of nitrogen permeases at the level of the endoplasmic reticulum. Involved in cell kill provoked by cisplatin and doxorubicin.

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Product Notes

The NPR2 npr2 (Catalog #AAA2521264) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPR2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NPR2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the NPR2 npr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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