Rabbit NPBWR1 / GPR7 Polyclonal Antibody | anti-NPBWR1 antibody

Rabbit Polyclonal to Human NPBWR1 / GPR7

Cat. Num. AAA247084

• Gene Names: NPBWR1; GPR7
• Reactivity: Gibbon, Gorilla, Human; Predicted Reactivity: Monkey, Mouse, Rat, Bovine, Horse (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: NPBWR1 / GPR7; Polyclonal Antibody; Rabbit Polyclonal to Human NPBWR1 / GPR7; Anti-NPBWR1 / GPR7 Antibody (Extracellular Domain) IHC-plus; NPBWR1; G protein-coupled receptor 7; GPR7; Neuropeptide B/W receptor 1; Neuropeptides B/W receptor 1; G-protein coupled receptor 7; Human NPBWR1; anti-NPBWR1 antibody

• Host: Rabbit
• Reactivity: Gibbon, Gorilla, Human; Predicted Reactivity: Monkey, Mouse, Rat, Bovine, Horse (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human NPBWR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 328

• Applicable Applications for anti-NPBWR1 antibody: Immunohistochemistry (IHC - Paraffin)
• Application Notes: IHC-P (6 - 12 ug/ml)
• Target Species: Human
• Immunogen Description: Synthetic 19 amino acid peptide from 2nd extracellular domain of human NPBWR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant, Panda (100%); Marmoset, Mouse, Rat, Bovine, Horse (95%); Rabbit (84%).
• Immunogen Type: Synthetic peptide
• Immunogen: NPBWR1 / GPR7 antibody was raised against synthetic 19 amino acid peptide from 2nd extracellular domain of human NPBWR1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant, Panda (100%); Marmoset, Mouse, Rat, Bovine, Horse (95%); Rabbit (84%).
• Antigen Modification: Extracellular Domain
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-NPBWR1 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-NPBWR1 / GPR7 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-NPBWR1 / GPR7 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-NPBWR1 antibody

GPR7 is a Neuropeptide Receptor GPCR. GPR7 is implicated in the regulation of feeding, neuroendorine system, memory, and learning.

Product Categories/Family for anti-NPBWR1 antibody

Family: GPCR; Subfamily: Neuropeptide

NCBI and Uniprot Product Information

• NCBI GI #: 53828924
• NCBI GeneID: 2831
• NCBI Accession #: NP_005276.2
• NCBI GenBank Nucleotide #: NM_005285.3
• UniProt Accession #: P48145; Q6NTC7
• Molecular Weight: 36,103 Da
• NCBI Official Full Name: neuropeptides B/W receptor type 1
• NCBI Official Synonym Full Names: neuropeptides B/W receptor 1
• NCBI Official Symbol: NPBWR1
• NCBI Official Synonym Symbols: GPR7
• NCBI Protein Information: neuropeptides B/W receptor type 1; neuropeptide B/W receptor 1; G protein-coupled receptor 7; G-protein coupled receptor 7; opioid-somatostatin-like receptor 7
• UniProt Protein Name: Neuropeptides B/W receptor type 1
• Protein Family: Neuropeptides B/W receptor
• UniProt Gene Name: NPBWR1
• UniProt Synonym Gene Names: GPR7
• UniProt Entry Name: NPBW1_HUMAN

Uniprot Description

NPBWR1: Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p22-q21.13

Cellular Component: neuron projection; integral to plasma membrane; integral to membrane; plasma membrane

Molecular Function: neuropeptide binding; protein binding; neuropeptide receptor activity; opioid receptor activity

Biological Process: synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; regulation of metabolic process