Western Blot (WB)
(Western BlotPositive WB detected in:Mouse liver tissue,Mouse kidney tissue,Mouse brain tissue,Mouse stomach tissueAll lanes: NOTUM antibody at 2.7ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 56 kDaObserved band size: 56 kDa)
Rabbit anti-Human, Mouse NOTUM Polyclonal Antibody | anti-NOTUM antibody
NOTUM Antibody
Gene Names
NOTUM; hNOTUM
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
>95%, Protein G purified
Synonyms
NOTUM; Polyclonal Antibody; NOTUM Antibody; Palmitoleoyl-protein carboxylesterase NOTUMCurated; hNOTUM1; anti-NOTUM antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
496
Applicable Applications for anti-NOTUM antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1: 500-1: 5000
Immunogen
Recombinant Human Palmitoleoyl-protein carboxylesterase NOTUM protein (100-235AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-168788
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Western Blot (WB)
(Western BlotPositive WB detected in:Mouse liver tissue,Mouse kidney tissue,Mouse brain tissue,Mouse stomach tissueAll lanes: NOTUM antibody at 2.7ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 56 kDaObserved band size: 56 kDa)
Western Blot (WB)
(Western BlotPositive WB detected in:Mouse liver tissue,Mouse kidney tissue,Mouse brain tissue,Mouse stomach tissueAll lanes: NOTUM antibody at 2.7ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 56 kDaObserved band size: 56 kDa)
Related Product Information for anti-NOTUM antibody
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleylation of WNT proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors (PubMed: 25731175).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,699 Da
NCBI Official Full Name
palmitoleoyl-protein carboxylesterase NOTUM
NCBI Official Synonym Full Names
NOTUM, palmitoleoyl-protein carboxylesterase
NCBI Official Symbol
NOTUM
NCBI Official Synonym Symbols
hNOTUM
NCBI Protein Information
palmitoleoyl-protein carboxylesterase NOTUM
UniProt Protein Name
Palmitoleoyl-protein carboxylesterase NOTUM
Protein Family
UniProt Gene Name
NOTUM
UniProt Entry Name
NOTUM_HUMAN
Uniprot Description
NOTUM: May deacetylate GlcNAc residues on cell surface glycans (Potential). Belongs to the pectinacetylesterase family.
Protein type: EC 3.-.-.-; Hydrolase; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: extracellular region
Molecular Function: phospholipase C activity
Biological Process: negative regulation of Wnt receptor signaling pathway
Research Articles on NOTUM
Similar Products
Product Notes
The NOTUM notum (Catalog #AAA7050490) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOTUM Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NOTUM can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1: 500-1: 5000. Researchers should empirically determine the suitability of the NOTUM notum for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOTUM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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