Testing Data
Rabbit NOTCH 1 Polyclonal Antibody | anti-NOTCH 1 antibody
Anti-NOTCH 1 Antibody
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Purified
Synonyms
NOTCH 1; Polyclonal Antibody; Anti-NOTCH 1 Antibody; Anti-Notch1 Antibody; anti-NOTCH 1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Notch1 antibody detects endogenous levels of Notch1 protein. Not tested with other proteins
Purity/Purification
Purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Applicable Applications for anti-NOTCH 1 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Recommended dilutions:
Peptide ELISA: 1:160,000
WB: 1:500 - 1:1000
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Peptide ELISA: 1:160,000
WB: 1:500 - 1:1000
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Synthetic peptide conjugated to KLH
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Testing Data
Testing Data
Related Product Information for anti-NOTCH 1 antibody
The Notch gene belongs to a family of epidermal growth factor (EGF) like homeotic genes, which encode transmembrane proteins with a variable number of cysteine rich EGF like repeats in the extracellular region. Four notch genes have been described in mammals: Notch1, Notch2, Notch3 and Notch4(Int3), which have been implicated in the differentiation of the nervous system and other structures. The EGF like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF like repeats and a transmembrane subunit including intracellular region (Ntm).
References
Lefort,K., Mandinova,A., Ostano,P., et al. Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases. Genes Dev. 21 (5), 562-577 (2007)
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Product Notes
The NOTCH 1 (Catalog #AAA415888) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NOTCH 1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NOTCH 1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Recommended dilutions: Peptide ELISA: 1:160,000 WB: 1:500 - 1:1000 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the NOTCH 1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOTCH 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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