Western Blot (WB)
Rabbit anti-Human annexin A6 Polyclonal Antibody | anti-ANXA6 antibody
Anti-annexin A6 Antibody
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Protein A purified
Synonyms
annexin A6; Polyclonal Antibody; Anti-annexin A6 Antibody; Anti-Annexin VI Antibody; anti-ANXA6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Annexin VI antibody detects endogenous levels of Annexin VI protein. Not tested with other proteins
Purity/Purification
Protein A purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
673
Applicable Applications for anti-ANXA6 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Recommended dilutions:
Peptide ELISA: 1:20,000
WB: 1:200 - 1:1000
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Peptide ELISA: 1:20,000
WB: 1:200 - 1:1000
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Synthetic peptide conjugated to KLH
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-ANXA6 antibody
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis
References
Barel,M., Gauffre,A., Lyamani,F.,et,al Intracellular interaction of EBV/C3d receptor (CR2) with p68, a calcium-binding protein present in normal but not in transformed Blymphocytes
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
75,907 Da
NCBI Official Full Name
annexin A6
NCBI Official Synonym Full Names
annexin A6<
NCBI Official Symbol
ANXA6
NCBI Protein Information
annexin A6; annexin VI; annexin-6
UniProt Protein Name
Annexin A6
Protein Family
UniProt Gene Name
ANXA6
UniProt Entry Name
ANXA6_BOVIN
Uniprot Description
ANXA2: a calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. Heterotetramer containing 2 light chains of S100A10 2 heavy chains of ANXA2. May cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
Protein type: Lipid-binding; Motility/polarity/chemotaxis; Calcium-binding
Cellular Component: basement membrane
Molecular Function: phospholipase inhibitor activity; calcium-dependent phospholipid binding; cytoskeletal protein binding; calcium ion binding
Biological Process: negative regulation of catalytic activity
Research Articles on ANXA6
Similar Products
Product Notes
The ANXA6 anxa6 (Catalog #AAA416264) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-annexin A6 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's annexin A6 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Recommended dilutions: Peptide ELISA: 1:20,000 WB: 1:200 - 1:1000 Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the ANXA6 anxa6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "annexin A6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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